SynchroMed™ II intrathecal pump Intrathecal drug infusion system for chronic pain management

The SynchroMed™ II programmable, implantable pump delivers drug to the intrathecal space via an implanted catheter. SynchroMed™ II pumps can be managed using the Control Workflow™ approach, which is designed to help eliminate systemic opioids and provide effective pain relief.

See Control Workflow™
 SynchroMed™ II intrathecal pump



Discover the SynchroMedTM II pump

Targeted drug delivery is a safe, proven, and effective way to manage chronic pain with fewer side effects and lower doses than systemic medication.1

Watch the animation to learn more. (2:24)

How SynchroMedTM II works

The drug enters the pump through the reservoir fill port and passes through the reservoir valve and into the SynchroMed™ II pump reservoir. At normal body temperatures, pressurized gas that is stored below the reservoir expands, exerting pressure on the reservoir. The pressure helps advance the drug into the SynchroMed™ II pump tubing.

The peristaltic action of the SynchroMed™ II pump moves the drug from the pump reservoir, through the pump tubing, check valve, catheter access port, and implanted catheter, to the infusion site.

The catheter access port (CAP) allows injection of the drug into the implanted catheter for drug administration and diagnostic purposes. Drug injected into the CAP bypasses the SynchroMed™ II pump mechanism and goes through the catheter port into the implanted catheter to the infusion site.

More SynchroMedTM II videos

Why recommend targeted drug delivery? - (05:57)

Product details

SynchroMedTM II pump

  • Offered in two sizes (20 mL or 40 mL) to create efficient refill intervals
  • Powerful long-lasting durability with diamond-like carbon coating that resists the wear from gear revolutions*
  • Designed to last up to 7 years at up to 0.9 mL/Day flow rate
  • +/-0.3% repeatability - each pump precisely delivers a reliable and consistent amount of drug**
  • Allows safe full-body access to 1.5- and 3.0-Tesla MRI.*** The pump is designed to resume programmed therapy after the scan and does not need to be emptied prior to a scan, minimizing drug waste and procedural steps.
Ports and suture loops on the SynchroMed™ II infusion pump

AscendaTM Catheter

  • Available in two lengths
  • Flexible construction with the ability to trim to the desired length
  • Unique four-layer construction for compression resistance
  • Sutureless connector
Close up of the Ascenda catheter.

*Medtronic data on file

**95% confidence, 50% of the pumps have a flow rate repeatability of +/- 0.27% between suuccessive 1 mL dispensed volumes within a refill cycle MRI Triangle

***  Under specific conditions for 1.5 T and 3.0 T MRI scans. Refer to product labeling.

†  Requires interrogation to confirm pump status.

Product reliability

Product Performance Data
See prospective, long-term multi-center registry study data for intrathecal drug delivery systems

Take a look inside the Medtronic SynchroMed™ II Pump
Enhanced design with increased reliablity

SynchroMed™ II Programmable Pump - Introduction and Evidence - (02:29)

SynchroMed™ II Programmable Pump - Motor Shaft Updates - (02:22)

SynchroMed™ II Programmable Pump - Gear Wheel and Feedthrough Updates - (03:06)

SynchroMed™ II Programmable Pump - Battery Coating Updates - (01:53)

SynchroMed™ II is indicated for chronic intrathecal infusion of Infumorph® preservative-free morphine sulfate sterile solution in the treatment of chronic intractable pain, Prialt® chronic intrathecal infusion of preservative-free ziconotide sterile solution for the management of severe chronic pain, and chronic intrathecal infusion of Lioresal® Intrathecal (baclofen injection) for the management of severe spasticity. Use of drugs outside these approved indications is off-label.

The use of off-label drugs is known to reduce pump reliability over implant life and may result in a return of underlying symptoms, drug withdrawal symptoms, or a clinically significant or fatal drug underdose. Medtronic's latest reliability data can be found in our Product Performance Report, comprised of data from Medtronic's prospective, long-term multi-center registry, at

Compatible products and software

Clinician Programmer

The SynchroMed™ II clinician programmer provides a simple, guided workflow approach to programming SynchroMed™ II intrathecal pumps.

myPTMTM personal therapy manager

The myPTM™ personal therapy manager works with the SynchroMed™ II pump to help alleviate unpredictable pain.

EfficioTM management software

Efficio™ management software is designed to simplify your pump practice by offering efficient schedule planning, simple drug tracking, historical dosing insights, and on-demand access to reports.

Model specifications

Model Battery Life

8637-20 (20 mL reservoir)

4 to 7 years

8637-40 (40 mL reservoir)

4 to 7 years


U.S. Clinician Services


Educational resources

Find educational tools and resources at Medtronic Academy. Learn more about the Dr. Lisa Stearns Academy for treating cancer pain.


Hamza M, Doleys D, Wells M, et al. Prospective study of 3-year follow-up of low dose intrathecal opioids in the management of chronic nonmalignant pain. Pain Med. 2012;13:1304-1313.