SynchroMed™ III Implantable infusion system
SynchroMed™ III is an implantable drug delivery system that helps manage chronic pain, cancer pain, and severe spasticity.
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Overview
Simple, safe, and effective intrathecal therapy
Unlike medications that must be absorbed systemically and must cross the blood-brain barrier to reach the receptors on the spinal cord to be effective, an implanted SynchroMed™ III programmable pump and catheter deliver prescribed amounts of medication directly into the cerebrospinal fluid in the intrathecal space bypassing the blood-brain barrier.
Targeted drug delivery (TDD) into the intrathecal space offers effective relief at a fraction of the systemic dose, which can reduce side effects.1-4
Product details
SynchroMed™ III pump
This system features a new REFILL ONLY physician workflow for more efficient programming, additional protections for patient data through enhanced cybersecurity, and improved electronics capable of delivering firmware upgrades to implanted devices going forward.
Together, these enhancements within the SynchroMed™ III system offer a enhanced platform compared to use of the SynchroMed™ II system.
Allows full-body 1.5 and 3T MRI† scans under specific conditions
SynchroMed™ III continues to provide peace of mind with proven durable design enhancements built in.‡
2011
Battery coating
added
2015
Gear wheel 3 material change
2015
Feedthroughs encapsulated
2017
Diamond-like carbon (DLC) coating added
Ascenda™ catheter
- Available in two lengths
- Flexible construction with the ability to trim to the desired length
- Unique four-layer construction for compression resistance
- Sutureless connector
Compatible products
SynchroMed™ Clinician Programmer
The SynchroMed™ clinician programmer provides a simple, guided workflow approach to programming SynchroMed™ implantable pumps.
myPTM™ Personal Therapy Manager
The myPTM™ personal therapy manager works with the SynchroMed™ pump to help alleviate unpredictable pain by enabling on-demand intrathecal boluses.
Efficio™ Management Software
The Efficio™ management software is designed to simplify your pump practice by offering efficient schedule planning, simple drug tracking, historical dosing insights, and on-demand access to reports.
Ordering information
| Item | Description |
| SynchroMed™ III pump (8667-20 and 8667-40) | SynchroMed™ III pump with 20 mL and 40 mL reservoir capacities, both redesigned with new electronics and firmware to enhance cybersecurity and enable upgradability. |
| SynchroMed™ Clinician Programmer CT900 tablet with A810 software v2.x | Clinician programmer with new refill-only workflow that streamlines clinician programming. |
| TH90T01 myPTM™ Personal Therapy Manager with A820 software v2.x | myPTM™ Personal Therapy Manager with updates to clarify clinician restrictions for patient bolus activation. |
Product portfolio
Medtronic has a decades-long history of creating implantable drug delivery system for pain relief.
Education & training
Learn more about targeted drug therapy for chronic pain.
Clinical evidence
See the results of our ongoing commitment to research.
† 
Under specific conditions. Refer to product labeling for full list of conditions: https://manuals.medtronic.com/manuals/mri/region
‡ Source: 2022 TDD Product Performance Report
1
Hamza, M et al. Prospective Study of 3-Year Follow-Up of Low-Dose Intrathecal Opioids in the Management of Chronic Nonmalignant Pain. Pain Medicine. (United States) 13, 1304–1313 (2012).
2
Smith, TJ et al. Randomized clinical trial of an implantable drug delivery system compared with comprehensive medical management for refractory cancer pain: Impact on pain, drug-related toxicity, and survival. Journal of Clinical Oncology. 20, 4040–4049 (2002).
3
Rushton, DN. Upper Motor Neurone Syndrome and Spasticity: Chapter 10 Intrathecal Baclofen for the Control of Spinal and Supraspinal Spasticity. ed. Barnes, MP and Johnson, GR pages 181–192. (Cambridge University Press, 2008). doi:10.1017/cbo9780511544866.011.
4
Deer, T et al. Intrathecal drug delivery for treatment of chronic low back pain: Report from the National Outcomes Registry for Low Back Pain. Pain Medicine. 5, 6–13 (2004).