Commitment to Quality Neuromodulation Product Performance

Medtronic's commitment to quality has long been stated in our mission, "To strive without reserve for the greatest possible reliability and quality in our products; to be the unsurpassed standard of comparison and to be recognized as a company of dedication, honesty, integrity, and service."

In line with this commitment we remain focused on sharing information and appropriate updates with customers on a regular basis. Thus, we are pleased to share the 10th Annual Medtronic Neurostimulation and Targeted Drug Delivery Systems Product Performance Report.

We are proud of our pioneering history at Medtronic and we realize the responsibility that comes with driving innovation in technology. As the first and only company to offer a full line of Spinal Cord Stimulation, Deep Brain Stimulation, Sacral Neuromodulation and Targeted Drug Delivery Systems therapies, we believe that performance reporting is even more important. We strive for better performance with every new product we develop. This report shows the evolution of product performance over time and also reveals advances in therapies that come with this experience and knowledge. Through this sharing of information, we can enable physicians to best leverage state-of-the-art therapy delivery and also understand the performance of our devices to best manage patients.

We have tracked over 16,500 patients in our ongoing post-market registry. The registry has enrolled over 50,000 neuromodulation system components. Components include pumps, catheters, neurostimulators, leads, and extensions. Data on other events not directly attributed to product performance are also included to provide additional information that may be important for patient management. Although gastric stimulation also involves neurostimulation, the performance of these systems is not included in the registry.

We welcome your suggestions on content, format, and any information you may have regarding the performance of Medtronic products. If you have questions or comments, please contact us through the information provided on the next page.

Thank you for your support.

Todd Weaver, PhD, MPH
Senior Clinical Research Manager, Data Science
Medtronic