Adaptix™ interbody system offers a robust design for increased strength,1 easy insertion, subsidence resistance,2,3 and incorporates Titan nanoLOCK™ surface technology for proven bone growth.*DOWNLOAD DATA
The Adaptix™ titanium spinal cage combines the trusted features of the Capstone™ spinal system, with several design enhancements.
1. Honeycomb Structure
2. Open Graft Windows
3. Dolphin Nose
4. Lateral Windows
5. Implant Width of 10mm
Titan nanoLOCK™ surface technology is created through a subtractive manufacturing process that removes material to enable a proprietary blend of surfaces at the macro, micro, and nano levels on every surface of the implant.
Inspired by nature, this surface technology uses "biomimicry" of osteoclastic pit geometry to mimic structures involved in the bone remodeling process.
Driven by science, Titan nanoLOCK™ surface technology emerged from a research-first approach to development. Multiple peer-reviewed in vitro studies resulted in Titan nanoLOCK surface technology being the first to demonstrate the elements to be considered in nanotechnology as outlined by the FDA.4
Download the latest peer-reviewed articles:
The navigated Adaptix™ interbody system integrates with the StealthStation™ navigation and O-arm™ imaging systems to enable pre-surgical planning, real-time navigation, and other benefits including virtual sizing of the spinal implant, 3D implant placement visualization, and confirmation of implant placement using the Surgical Synergy™ workflow.
Comparison of Adaptix and Capstone testing per ASTM F2077and ASTM F2267
Based on surface area measurement
Based on engineering principles
FDA Guidance, Considering Whether an FDA-Regulated Product Involves the Application of Nanotechnology
Based on six peer-reviewed, published in vitro studies on Titan surface technology:
I. Matteson, J.L., Greenspan, D.C., Tighe, T.B., Gilfoy, N., Stapleton, J.J. Assessing the hierarchical structure of titanium implant surfaces. J Biomed Mater Res B. [In Press] EPub29 May 2015.
II. Olivares-Navarrete, R., HyzyS.L., Gittens, R.A., Schneider, J.M., Haithcock, D., Ullrich, P., Schwartz, Z., Boyan, B.D. Rough titanium alloys regulate osteoblast production of angiogenic factors. Spine J. 2013 Nov; 13(11):1563-70.
III. Gittens, R.A., Olivares-Navarrete, R., Schwartz, Z., Boyan, B.D. Implant osseointegration and the role of microroughness and nanostructures: Lessons for spine implants. Acta Biomater 2014 Aug; 10(8): 3363-3371.
IV. Olivares-Navarrete, R., HyzyS.L., Gittens, R.A., Berg, M.E., Schneider, J.M., Hotchkiss, K., Schwartz, Z., Boyan, B. D. Osteoblast lineage cells can discriminate microscale topographic features on titanium-aluminum-vanadium surfaces. Ann Biomed Eng. 2014 Dec; 42(12): 2551-61.
V. Olivares-Navarrete, R., HyzyS.L., Slosar, P.J., Schneider, J.M., Schwartz, Z., Boyan, B.D. Implant materials generate different peri-implant inflammatory factors: PEEK promotes fibrosis and micro-textured titanium promotes osteogenic factors. Spine. 2015 Mar; 40(6): 399-404.
VI. Banik, B., Riley, T., Platt, C., Brown, J. Human mesenchymal stem cell morphology and migration on microtextured titanium. Front Bioeng Biotechnol. 2016 May; 4(41) doi: 10.3389/fbioe.2016.00041.