To determine whether long-term cardiac monitoring is superior to usual care for AF detection in patients with stroke attributed to large or small vessel disease through 12 months of follow-up
Compare incidence rates of AF between study arms through 36 months of follow-up
Reveal LINQ ICM detected significantly higher rates of AF in large and small vessel stroke patients when compared to site-specific usual care.
12.1% (n = 27) in the Reveal LINQ ICM arm versus 1.8% (n = 4) in the control group.
Approximately 1 in 8 patients in the ICM arm had AF detected.
At 12 months, 96.3% (n = 27) of first AF episodes were asymptomatic in the ICM arm.
The majority of patients (55.5%, n = 27) with AF detected in the ICM arm had an episode lasting greater than one hour.
Bernstein RA, Kamel H, Granger CB, et al. for the STROKE AF Investigators. Effect of Long-term Continuous Cardiac Monitoring vs Usual Care on Detection of Atrial Fibrillation in Patients With Stroke Attributed to Large- or Small-Vessel Disease. JAMA. Published online June 1, 2021. doi:10.1001/jama.2021.6470.