The Titan Endoskeleton surface uses subtractive manufacturing to create unique textures at the macro and micro levels.
Anti-expulsion texturing on superior and inferior surfaces.
The micro level (10-6m) features osteoclastic-sized pits on all external and interior surfaces.
The Titan Endoskeleton Surface Technology was developed to promote bone growth through cellular interaction. This breakthrough inspired a revolution in surface technology, leading directly to a proprietary combination of textures that altered the interbody fusion market. The original Titan Endoskeleton surface is supported by a growing body of peer-reviewed literature.
Titan introduces its first generation surface technology for titanium interbodies to the market.
Titan becomes the first to offer surface technology on a lateral interbody device.
Titan Original Surface wins the IMAST Whitecloud Award for Best Basic Science.
Titan is the first to gain FDA nanotechnology clearance for spine.
Titan Original Surface wins an OTW Best Technology Award.
Titan gains a Nanotechnology New Technology code from CMS.
Titan becomes the first to commercialize nanotechnology for the spine.
Titan completes the first nanoLOCK™ case.
Medtronic and Titan join forces.
Olivares-Navarrete, R., Hyzy S.L., Gittens, R.A., Schneider, J.M., Haithcock, D., Ullrich, P., Schwartz, Z., Boyan, B.D. Rough titanium alloys regulate osteoblast production of angiogenic factors. Spine J. 2013 Nov; 13(11):1563-70.
Olivares-Navarrete, R., Hyzy S.L., Slosar, P.J., Schneider, J.M., Schwartz, Z., Boyan, B.D. Implant materials generate different peri-implant inflammatory factors: PEEK promotes fibrosis and micro-textured titanium promotes osteogenic factors. Spine. 2015 Mar; 40(6): 399-404.
Banik, B., Riley, T., Platt, C., Brown, J. Human mesenchymal stem cell morphology and migration on microtextured titanium. Front Bioeng Biotechnol. 2016 May; 4(41) doi: 10.3389/fbioe.2016.00041.