The Titan Endoskeleton surface uses subtractive manufacturing to create unique textures at the macro and micro levels.


Anti-expulsion texturing on superior and inferior surfaces.

Surface of Titan nanoLOCk at a macro level, with anti-expulsion texturing on superior and inferior surfaces.


The micro level (10-6m) features osteoclastic-sized pits on all external and interior surfaces.

Surface of Titan nanoLOCk at a micro level, with anti-expulsion texturing on superior and inferior surfaces.


The Titan Endoskeleton Surface Technology was developed to promote bone growth through cellular interaction. This breakthrough inspired a revolution in surface technology, leading directly to a proprietary combination of textures that altered the interbody fusion market. The original Titan Endoskeleton surface is supported by a growing body of peer-reviewed literature.



THe Evolution of Surface Technology

Timeline 1

February 2007
Titan introduces its first generation surface technology for titanium interbodies to the market.

Timeline 2

July 2014
Titan becomes the first to offer surface technology on a lateral interbody device.
Titan Original Surface wins the IMAST Whitecloud Award for Best Basic Science. 

Timeline 2

November 2014
Titan is the first to gain FDA nanotechnology clearance for spine.

Timeline 2

November 2015
Titan Original Surface wins an OTW Best Technology Award. 

Timeline 6

July 2016
Titan gains a Nanotechnology New Technology code from CMS. 

Timeline 1

August 2016
Titan becomes the first to commercialize nanotechnology for the spine.
Titan completes the first nanoLOCK™ case. 

Timeline 2

June 2019
Medtronic and Titan join forces. 

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Olivares-Navarrete, R., Hyzy S.L., Gittens, R.A., Schneider, J.M., Haithcock, D., Ullrich, P., Schwartz, Z., Boyan, B.D. Rough titanium alloys regulate osteoblast production of angiogenic factors. Spine J. 2013 Nov; 13(11):1563-70.


Olivares-Navarrete, R., Hyzy S.L., Slosar, P.J., Schneider, J.M., Schwartz, Z., Boyan, B.D. Implant materials generate different peri-implant inflammatory factors: PEEK promotes fibrosis and micro-textured titanium promotes osteogenic factors. Spine. 2015 Mar; 40(6): 399-404.


Banik, B., Riley, T., Platt, C., Brown, J. Human mesenchymal stem cell morphology and migration on microtextured titanium. Front Bioeng Biotechnol. 2016 May; 4(41) doi: 10.3389/fbioe.2016.00041.