TITAN ENDOSKELETON™ INTERBODY SCIENCE
Learn about the titanium surface technology that started a revolution in interbody performance.
SEE PRODUCTS
TWO LEVELS OF TEXTURE
The Titan Endoskeleton surface uses subtractive manufacturing to create unique textures at the macro and micro levels.
MACRO LEVEL
Anti-expulsion texturing on superior and inferior surfaces.
MiCRO LEVEL
The micro level (10-6m) features osteoclastic-sized pits on all external and interior surfaces.
DRIVING CELLULAR INTERACTION
The Titan Endoskeleton Surface Technology was developed to promote bone growth through cellular interaction. This breakthrough inspired a revolution in surface technology, leading directly to a proprietary combination of textures that altered the interbody fusion market. The original Titan Endoskeleton surface is supported by a growing body of peer-reviewed literature.
- Rough titanium alloys regulate osteoblast production of angiogenic factors1
- Implant materials generate different peri-implant inflammatory factors: PEEK promotes fibrosis and micro-textured titanium promotes osteogenic factors2
- Human mesenchymal stem cell morphology and migration on microtextured titanium3
THe Evolution of Surface Technology
February 2007
Titan introduces its first generation surface technology for titanium interbodies to the market.
July 2014
Titan becomes the first to offer surface technology on a lateral interbody device.
Titan Original Surface wins the IMAST Whitecloud Award for Best Basic Science.
November 2014
Titan is the first to gain FDA nanotechnology clearance for spine.
November 2015
Titan Original Surface wins an OTW Best Technology Award.
July 2016
Titan gains a Nanotechnology New Technology code from CMS.
August 2016
Titan becomes the first to commercialize nanotechnology for the spine.
Titan completes the first nanoLOCK™ case.
June 2019
Medtronic and Titan join forces.
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VIEW EVENTS
1
Olivares-Navarrete, R., Hyzy S.L., Gittens, R.A., Schneider, J.M., Haithcock, D., Ullrich, P., Schwartz, Z., Boyan, B.D. Rough titanium alloys regulate osteoblast production of angiogenic factors. Spine J. 2013 Nov; 13(11):1563-70.
2
Olivares-Navarrete, R., Hyzy S.L., Slosar, P.J., Schneider, J.M., Schwartz, Z., Boyan, B.D. Implant materials generate different peri-implant inflammatory factors: PEEK promotes fibrosis and micro-textured titanium promotes osteogenic factors. Spine. 2015 Mar; 40(6): 399-404.
3
Banik, B., Riley, T., Platt, C., Brown, J. Human mesenchymal stem cell morphology and migration on microtextured titanium. Front Bioeng Biotechnol. 2016 May; 4(41) doi: 10.3389/fbioe.2016.00041.