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OSTEOCOOL RF ABLATION for the treatment of painful bone tumors

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Investing in your expertise and our innovation

The OsteoCool™ Post-Market Clinical Study (OPuS One) is one of the largest studies in RF ablation evaluating outcomes in patients with painful metastatic tumors and benign bone tumors. This multicenter study is collecting real world evidence on the effectiveness and safety of OsteoCool. OPuS One is a prospective, non-randomized, single-arm study, enrolling up to 250 patients globally.

Watch the interview with primary investigators, Drs. Jason Levy and Sandeep Bagla.

Patient Feature

Cory's Story

Cory’s breast cancer metastasized to her spine and sacrum causing unrelenting lower back pain that brought her into the ER. Not wanting to remain on opioids for her pain, Cory asked her doctor about other options. Dr. Ramsin Benyamin at Millennium Pain Center in Normal, IL offered to treat Cory’s cancer pain with OsteoCool.

Learn how the OsteoCool procedure affected Cory’s quality of life.

Product Overview

The OsteoCool RF Ablation system is cooled radiofrequency (RF) ablation technology. It offers simultaneous, dual-probe capabilities for treating painful bone tumors, including benign and painful metastatic lesions. The system’s algorithms are designed to perform optimally in bone, allowing you to overcome challenges through a wide range of ablation scenarios, letting you treat patients confidently and consistently.

Watch the OsteoCool RF Ablation System Procedure Animation
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Indications, Safety, and Warnings


  • Intended for palliative treatment in spinal procedures by ablation of metastatic malignant lesions in a vertebral body
  • Coagulation and ablation of tissue in bone during surgical procedures including palliation of pain associated with metastatic lesions involving bone in patients who have failed or are not candidates for standard therapy
  • Ablation of benign bone tumors such as osteoid osteoma


  • As a consequence of electrosurgery, damage to surrounding tissue through iatrogenic injury could occur
  • Pulmonary embolism