Percutaneous tibial neuromodulation (PTNM) delivered by the NURO™ system is a safe and effective treatment for incontinence symptoms caused by overactive bladder (OAB).1-3 It's proven to restore* bladder function without the side effects of medication.†,4

How PTNM Works

The NURO system delivers electrical pulses through a needle to stimulate the afferent fibers of the tibial nerve that runs posterior to the medial malleolus and extends to the sacral nerve plexus. This treatment is called PTNM, otherwise known as percutaneous tibial neurostimulation (PTNS).

  • Evidence links OAB to dysfunctional bladder-central nervous system (CNS) communication.5
  • PTNM is thought to restore* bladder function by modulating the bladder-CNS communication pathway.
  • The therapy uses an adjustable electrical pulse to directly stimulate the peripheral tibial nerve, indirectly thought to modulate communication with the CNS to relieve symptoms of OAB, helping patients take back control.

PTNM with the NURO System - (05:28)

Watch an animation illustrating how to deliver percutaneous tibial neuromodulation therapy with the NURO system.
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Designed to meet the needs of senior living facilities, the NURO system delivers therapy to your OAB patients efficiently and cost-effectively. Its portability allows you to administer therapy in the comfort and privacy of the resident’s room.


The resident is typically treated once per week for 30 minutes for a period of 12 weeks. No decision regarding therapy effectiveness should be made until the patient completes the 12 therapy sessions.

For residents responding to treatment, the time between therapy sessions may be slowly increased after the initial 12 therapy sessions, with the resident closely monitored for the return of symptoms. If symptoms reappear or increase in severity, the resident’s treatment schedule should revert to the last previously effective treatment schedule.

Medtronic PTNM Therapy Sequence and Benefits - (02:11)

Dr. Colin Goudelocke outlines the PTNM therapy sequence and describes its benefits for senior living facilities.
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Percutaneous Tibial Neuromodulation (PTNM) with the NURO System

This course provides a brief overview of advanced treatment options for OAB and a comprehensive introduction to the NURO system.


Restored bladder function is defined as a measurable reduction in urinary frequency and/or urinary incontinence episodes following treatment.

Most common side effects are temporary and include mild pain or skin inflammation at or near the stimulation site.


Peters KM, Carrico DJ, Perez-Marrero RA, et al. Randomized trial of percutaneous tibial nerve stimulation versus sham efficacy in the treatment of overactive bladder syndrome: results from the SUmiT trial. J Urol. 2010;183(4):1438-1443.


Finazzi-Agrò E, Campagna A, Sciobica F, et al. Posterior tibial nerve stimulation: is the once-a-week protocol the best option? Minerva Urol Nefrol. 2005;57(2):119-123.


Govier FE, Litwiller S, Nitti V, et al. Percutaneous afferent neuromodulation for the refractory overactive bladder: results of a multicenter study. J Urol. 2001;165(4):1193-1198.


Peters, K. M., S. A. Macdiarmid, et al. Randomized trial of percutaneous tibial nerve stimulation versus extended-release tolterodine: results from the overactive bladder innovative therapy trial. J Urol 2009; 182(3): 1055-1061.


Leng WW, Morrisroe SN. Sacral nerve stimulation for the overactive bladder. Urol Clin N Am. 2006;33:491-501.