Benefits and risks

The Medtronic Symplicity blood pressure procedure may help reduce high blood pressure (hypertension),1,2 which is shown to lower your risk of heart attacks, strokes, and other serious health problems.3


Illustration of a patient lying in a hospital bed while hooked up to an ECG with a female physician standing nearby


Reducing blood pressure by 10 mmHg can lower your risk of 3:

heart failure


cardiovascular events





Illustrated pink and white pill in a left hand and a cup of water in a right hand

Beyond another daily blood pressure pill

While it may not affect how many medications you take, the Symplicity blood procedure is a complementary treatment option and may help reduce high blood pressure1,2 with the potential to not need to add another pill to your daily regimen.

Treatment beyond blood pressure medications

The Symplicity blood pressure procedure is proven to safely help lower blood pressure in people who are taking blood pressure medication and those who are not.1,2


What are the risks of the Symplicity blood pressure procedure?

The Medtronic Symplicity blood pressure procedure does have known risks. These risks should be considered in relation to the potential benefits of the procedure.

It's important to talk with your doctor about the benefits and risks.

Not every person will experience the same results.

Is the Symplicity blood pressure procedure right for you?

Answer a few simple questions then talk to your doctor to see if the procedure may be right for you.

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Find a Symplicity specialist.

Here’s how you can find a doctor near you who is experienced in the Symplicity blood pressure procedure.

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Contact us to receive the latest information about the Symplicity blood pressure procedure.


Studies focused on 388 people on and off medications.



Kandzari DE, Townsend RR, Kario K, et al. Safety and Efficacy of Renal Denervation in Patients Taking Antihypertensive Medications. J Am Coll Cardiol. November 7, 2023;82(19):1809–1823.


Böhm M, Kario K, Kandzari DE, et al. Efficacy of catheter-based renal denervation in the absence of antihypertensive medications (SPYRAL HTN-OFF MED Pivotal): a multicentre, randomized, sham-controlled trial. Lancet. May 2, 2020;395(10234):1444–1451.


Ettehad D, Emdin CA, Kiran A, et al. Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis. Lancet. March 5, 2016;387(10022):957–967.


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