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Medtronic / Covidien Products / Brain Monitoring / Bispectral Index™ (BIS™) Monitoring System

BIS™ technology

Proven algorithm. Trusted insight.

Too much or too little anesthesia can be associated with challenges such as longer recovery times and postoperative neurocognitive disorders. The BIS™ technology reflects the anesthetic effect on each patient’s brain which helps you to personalize dosing to improve emergence and recovery times.1–4

  • Use up to 38% less anesthetic agent.1,5–6
  • Patients monitored with BIS™ technology have been shown to wake up 27–53% faster in the OR.1,7–9
  • Postoperative delirium is reduced up to 29%.10

Features

BIS™ complete 4-channel and 2-channel monitors

The BIS™ monitor translates the raw EEG data into the easy-to-read BIS™ index.

Both 2-channel and 4-channel monitors provide:

  • User-configurable display
  • Versatile platform for future expandability

 

The 4-channel monitor provides:

  • Four-channel EEG monitoring
  • Asymmetry indicator (ASYM)
  • Ability to trend BIS™-left and BIS™-right values
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Order Information
ORDER CODE DESCRIPTION UNIT OF MEASURE QUANTITY
186-1014 BIS™ Complete 4-Channel Monitoring System Each 1
186-0210 BIS™ Complete 2-Channel Monitor Each 1
186-0224-AMS BIS™ LOC 4-Channel Monitor with Patient Interface Cable (PIC-4) Each 1
186-0195-AMS BIS™ LOC 2-Channel Monitor with Patient Interface Cable Each 1
186-0212 BIS™ Bilateral Sensor Each 1
Specifications
DISPLAY BIS™ COMPLETE 2-CHANNEL MONITOR BIS™ COMPLETE 4-CHANNEL MONITORING SYSTEM
Parameters BIS, SQI, EMG, SR, BC, EEG BIS, SQI, EMG, SR, BC, TP, SEF, EEG
Trended parameters BIS, SQI, EMG, SR, BC BIS, SQI, EMG, SR, BC, SEF
BIS™ alarm Upper and lower limit, results in visual and audible alert when out of range Upper and lower limit, results in visual and audible alert when out of range

Order Information

See the evidence for the BIS™ proven algorithm.

A circular illustration representing 38 percent

Use up to 38% less anesthetic agents to help control cost.1, 5-8

A circular illustration representing a 27 to 53 percent range

Patients monitored with BIS™ technology have been shown to wake up 27–53% faster in the OR.1,7-9

A circular illustration representing 87 percent

87%  increase in “excellent/fully oriented” status on PACU admission.8

BIS™ Advance for TIVA

BIS™ Advance for Enhanced Recovery After Surgery

BIS™ Advance for postoperative delirium (POD)

Clinical evidence

Improved Post Anesthesia Recovery

“The pooled data showed that the use of BIS™ was significantly associated with a lower incidence of POCD and improved recovery parameters (extubation time, time to eye opening, and time to discharge from the PACU).”

– Wei Zhuen Chew et al, Bispectral Index™ (BIS™) Monitoring and Postoperative Delirium in Elderly Patients Undergoing Surgery: A Systematic Review and Meta-Analysis With Trial Sequential Analysis

Chew WZ, Teoh WY, Sivanesan N, San Loh P, Shariffuddin II, Ti LK, Ng KT. Bispectral index™ (BIS™) monitoring and postoperative delirium in elderly patients undergoing surgery: A systematic review and meta-analysis With trial sequential analysis. Journal of Cardiothoracic and Vascular Anesthesia. 2022 Dec 1;36(12):4449–59.

Improved post anesthesia neurocognitive outcomes

“We found that BIS™ monitoring of the depth of anesthesia prevented POD, whereas EEG monitoring was not effective. BIS™ quantifies the depth of anesthesia based on EEGs, which enables a more accurate control of anesthetic concentration and increases patient safely.”

– Xia Li et al, Effects of perioperative interventions for preventing postoperative delirium

Li X, Wang Y, Liu J, Xiong Y, Chen S, Han J, Xie W, Wu Q. Effects of perioperative interventions for preventing postoperative delirium: A protocol for systematic review and meta-analysis of randomized controlled trials. Medicine. 2021 Jul 7;100(29)

Intraoperative Awareness Prevention

“…in intravenous anesthesia, BIS™ monitoring could reduce the incidence of intraoperative awareness by approximately 80%.”

– Wen-Wei Gao, et al., in a clinical review on BIS™ monitoring on interoperative awareness

Gao, Ww., He, Yh., Liu, L. et al. BIS™ Monitoring on Intraoperative Awareness: A Meta-analysis. Curr Med Sci. 38, 349–353 (2018). https://doi.org/10.1007/s11596-018-1886-1

Educational opportunities

Access training portal

Brain monitoring training pathways

Listen to MedEd podcast

Interview-style discussions on anesthesia and the brain

Check MedEd Bytes

A “byte”-sized educational video series

Watch webinars

A library of brain monitoring webinars

Product training and support

Access in-service training videos, product guides, frequently asked questions, and other product support.

Product manuals

Find up-to-date product manuals in the brain monitoring section.

Reimbursement billing and coding guide

Get provider-specific billing and coding information for the BIS™ monitoring system.

Resources

 

Monograph

Optimizing care in TIVA procedures

Monograph

Integrating BIS™ Monitoring into enhanced recovery pathways

Monograph

BIS™ monitoring in older patients undergoing surgery

Related Products

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Sensor BIS™ Bilateral

Sensor BIS™ Bilateral
BIS™ Pediatric Sensor

BIS™ Pediatric Sensor

 

 

The BIS™ monitoring system should not be used as the sole basis for diagnosis or therapy and is intended only as an adjunct in patient assessment. Reliance on the BIS™ monitoring system alone for intraoperative anesthetic management is not recommended.

  • 1. Lewis SR, Pritchard MW, Fawcett LJ, Punjasawadwong Y. Bispectral index™ for improving intraoperative awareness and early postoperative recovery in adults. Cochrane Database Syst Rev. 2019;9:CD003843. doi:10.1002/14651858.CD003843.pub4.

  • 2. Zhang C, Xu L, Ma Y-Q, et al. Bispectral index™ monitoring prevent awareness during total intravenous anesthesia: a prospective, randomized, double-blinded, multi-center controlled trial. Chin Med J (Engl). 2011;124(22):3664–3669. 

  • 3. Myles PS, Leslie K, McNeil J, Forbes A, Chan MT. Bispectral index™ monitoring to prevent awareness during anaesthesia: The B-Aware randomised controlled trial. Lancet. 2004;363(9423):1757-1763. doi:10.1016/S0140-6736(04)16300–9.

  • 4. Ekman A, Lindholm ML, Lennmarken C, Sandin R. Reduction in the incidence of awareness using BIS™ monitoring. Acta Anaesthesiol Scand. 2004;48(1):20-26. doi:10.1111/j.1399–6576.2004.00260.x.

  • 5. Punjasawadwong Y, Phongchiewboon A, Bunchungmongkol N. Bispectral index™ for improving anaesthetic delivery and postoperative recovery. Cochrane Database Syst Rev. 2014;(6):CD003843. doi:10.1002/14651858.CD003843.pub3.

  • 6. Luginbuhl M, Wuthrich S, Petersen-Felix S, Zbinden AM, Schnider TW. Different benefit of bispectal index™ (BIS™) in desflurane and propofol anesthesia. Acta Anaesthesiol Scand. 2003;47(2):165–73.

  • 7. Song D, Joshi GP, White PF. Titration of volatile anesthetics using bispectral index™ facilitates recovery after ambulatory anesthesia. Anesthesiology. 1997;87(4):842–848.

  • 8. Gan TJ, Glass PS, Windsor A, et al. Bispectral index™ monitoring allows faster emergence and improved recovery … . Anesthesiology. 1997;87(4):808–815. doi:10.1097/00000542-199710000-00014.

  • 9. Wong J, Song D, Blanshard H, Grady D, Chung F. Titration of isoflurane using BIS™ index improves early recovery of elderly patients undergoing orthopedic surgeries. Can J Anaesth. 2002;49(1):13–18. doi:10.1007/BF03020413.

  • 10. Punjasawadwong Y, Chau-In W, Laopaiboon M, Punjasawadwong S, Pin-On P. Processed electroencephalogram and evoked potential techniques for amelioration of postoperative delirium and cognitive dysfunction following non-cardiac and non-neurosurgical procedures in adults. Cochrane Database Syst Rev. 2018;5:CD01128.

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