Too much or too little anesthesia can be associated with challenges such as longer recovery times and postoperative neurocognitive disorders. The BIS™ technology reflects the anesthetic effect on each patient’s brain which helps you to personalize dosing to improve emergence and recovery times.1–4
The BIS™ monitor translates the raw EEG data into the easy-to-read BIS™ index.
Both 2-channel and 4-channel monitors provide:
The 4-channel monitor provides:
Use up to 38% less anesthetic agents to help control cost.1, 5-8
Patients monitored with BIS™ technology have been shown to wake up 27–53% faster in the OR.1,7-9
87% increase in “excellent/fully oriented” status on PACU admission.8
“The pooled data showed that the use of BIS™ was significantly associated with a lower incidence of POCD and improved recovery parameters (extubation time, time to eye opening, and time to discharge from the PACU).”
– Wei Zhuen Chew et al, Bispectral Index™ (BIS™) Monitoring and Postoperative Delirium in Elderly Patients Undergoing Surgery: A Systematic Review and Meta-Analysis With Trial Sequential Analysis
Chew WZ, Teoh WY, Sivanesan N, San Loh P, Shariffuddin II, Ti LK, Ng KT. Bispectral index™ (BIS™) monitoring and postoperative delirium in elderly patients undergoing surgery: A systematic review and meta-analysis With trial sequential analysis. Journal of Cardiothoracic and Vascular Anesthesia. 2022 Dec 1;36(12):4449–59.
“We found that BIS™ monitoring of the depth of anesthesia prevented POD, whereas EEG monitoring was not effective. BIS™ quantifies the depth of anesthesia based on EEGs, which enables a more accurate control of anesthetic concentration and increases patient safely.”
– Xia Li et al, Effects of perioperative interventions for preventing postoperative delirium
Li X, Wang Y, Liu J, Xiong Y, Chen S, Han J, Xie W, Wu Q. Effects of perioperative interventions for preventing postoperative delirium: A protocol for systematic review and meta-analysis of randomized controlled trials. Medicine. 2021 Jul 7;100(29)
“…in intravenous anesthesia, BIS™ monitoring could reduce the incidence of intraoperative awareness by approximately 80%.”
– Wen-Wei Gao, et al., in a clinical review on BIS™ monitoring on interoperative awareness
Gao, Ww., He, Yh., Liu, L. et al. BIS™ Monitoring on Intraoperative Awareness: A Meta-analysis. Curr Med Sci. 38, 349–353 (2018). https://doi.org/10.1007/s11596-018-1886-1
The BIS™ monitoring system should not be used as the sole basis for diagnosis or therapy and is intended only as an adjunct in patient assessment. Reliance on the BIS™ monitoring system alone for intraoperative anesthetic management is not recommended.
1. Lewis SR, Pritchard MW, Fawcett LJ, Punjasawadwong Y. Bispectral index™ for improving intraoperative awareness and early postoperative recovery in adults. Cochrane Database Syst Rev. 2019;9:CD003843. doi:10.1002/14651858.CD003843.pub4.
2. Zhang C, Xu L, Ma Y-Q, et al. Bispectral index™ monitoring prevent awareness during total intravenous anesthesia: a prospective, randomized, double-blinded, multi-center controlled trial. Chin Med J (Engl). 2011;124(22):3664–3669.
3. Myles PS, Leslie K, McNeil J, Forbes A, Chan MT. Bispectral index™ monitoring to prevent awareness during anaesthesia: The B-Aware randomised controlled trial. Lancet. 2004;363(9423):1757-1763. doi:10.1016/S0140-6736(04)16300–9.
4. Ekman A, Lindholm ML, Lennmarken C, Sandin R. Reduction in the incidence of awareness using BIS™ monitoring. Acta Anaesthesiol Scand. 2004;48(1):20-26. doi:10.1111/j.1399–6576.2004.00260.x.
5. Punjasawadwong Y, Phongchiewboon A, Bunchungmongkol N. Bispectral index™ for improving anaesthetic delivery and postoperative recovery. Cochrane Database Syst Rev. 2014;(6):CD003843. doi:10.1002/14651858.CD003843.pub3.
6. Luginbuhl M, Wuthrich S, Petersen-Felix S, Zbinden AM, Schnider TW. Different benefit of bispectal index™ (BIS™) in desflurane and propofol anesthesia. Acta Anaesthesiol Scand. 2003;47(2):165–73.
7. Song D, Joshi GP, White PF. Titration of volatile anesthetics using bispectral index™ facilitates recovery after ambulatory anesthesia. Anesthesiology. 1997;87(4):842–848.
8. Gan TJ, Glass PS, Windsor A, et al. Bispectral index™ monitoring allows faster emergence and improved recovery … . Anesthesiology. 1997;87(4):808–815. doi:10.1097/00000542-199710000-00014.
9. Wong J, Song D, Blanshard H, Grady D, Chung F. Titration of isoflurane using BIS™ index improves early recovery of elderly patients undergoing orthopedic surgeries. Can J Anaesth. 2002;49(1):13–18. doi:10.1007/BF03020413.
10. Punjasawadwong Y, Chau-In W, Laopaiboon M, Punjasawadwong S, Pin-On P. Processed electroencephalogram and evoked potential techniques for amelioration of postoperative delirium and cognitive dysfunction following non-cardiac and non-neurosurgical procedures in adults. Cochrane Database Syst Rev. 2018;5:CD01128.