† Based on clinical and bench testing for expected therapy settings
‡ Under expected therapy settings and telemetry use
§Please see System Eligibility, Battery Longevity, Specifications manual for battery longevity estimates
From originator to innovator
The same passion that inspired us to originate neuromodulation for bladder and bowel control drives our innovation today.
Backed by 30 years of clinical data for urinary control conditions17 and 20 years of clinical data for bowel control.18
Fran’s Altaviva™ system story
Road trips. International travel. Cruises.
Not having to let my bladder
control me lets me go out
more… do more things.
It’s just the freedom.”
— Fran, Altaviva™ system patient
Individual results may vary.
This patient participated in the TITAN 2 clinical trial that studied the investigational tibial neuromodulation device and its use. For more information, visit clinicaltrials.gov: NCT05226286.
Morgon’s InterStim™ system story
Adventure. Time with loved ones.
InterStim™ has helped me feel better about my life… it continues to allow me to do the things I know I wouldn’t be able to do without it.”
— Morgon, InterStim™ system patient
Individual results may vary.
For stimulation devices, common risks may include surgical infection, pain, undesirable changes in urinary or bowel function, and uncomfortable stimulation. Refer to Important Safety Information for more details.
Time-tested results that change lives
#1 Sacral neuromodulation device choice globally for OAB and FI patients19
years of innovation
clinical
publications
patients treated with
InterStim™ systems
References
Stewart WF, Van Rooyen JB, Cundiff GW, et al. Prevalence and burden of overactive bladder in the United States. World J Urol. 2003;20(6):327-336.
Centers for Disease Control and Prevention (CDC). National Center for Health Statistics (NCHS). National Health and Nutrition Examination Survey Data, 2024. https://www.cdc.gov/nchs/nhanes/Default.aspx. Accessed January 31, 2025.
Whitehead WE, Borrud L, Goode PS, et al. Fecal Incontinence in US adults: epidemiology and risk factors. Gastroenterology. 2009;137(2):512-517.
Ditah I, Devaki P, Luma HN et al. Prevalence, trends, and risk factors for fecal incontinence in United States adults, 2005-2010. Clin Gastroenterol Hepatol. 2014;12:636-643.
Coyne KS, et al. The prevalence of chronic constipation and fecal incontinence among men and women with symptoms of overactive bladder. BJU Int. 2011 Jan;107(2):254-61.
M028930C001RevC - Altaviva™ Model P7850N Neurostimulator Implant Manual.
Cameron AP, Chung DE, Dielubanza EJ et al. The AUA/SUFU guideline on the diagnosis and treatment of idiopathic overactive bladder (2024). J Urol. 2024;212:11-20.
M028929C001RevC - Clinician Therapy and Programming Guide Altaviva™ Model P7850N.
Siegel S, Noblett K, Mangel J, et al. Five-year follow-up results of a prospective, multicenter study of patients with overactive bladder treated with sacral neuromodulation. J Urol. 2018;199(1):229-236.
Medtronic InterStim™ Clinical Summary 2018.
Hull T, Giese C, Wexner SD, Mellgren A, Devroede G, et al. Long-term durability of sacral nerve stimulation therapy for chronic fecal incontinence. DisColon Rectum. 2013;56:234–245.
NDHF1534-200202, Marketing claim data summary: Axonics vs Medtronic Basic Evaluation Lead, October 2020. Medtronic data on file.
Elterman D, Michaels J, Margolis E, et al. Prospective, multicenter study to evaluate performance and safety of a re‐engineered temporary lead for InterStim™ therapy evaluation. Neurourol Urodyn. 2022;1-8.
Medtronic MRI Guidelines for InterStim™ systems, M980291A032 Rev A.
Axonics™ MRI guidelines, US, 110-0092-001rAM. Updated February 2024.
Schmidt RA, Jonas U, Oleson KA, et al. Sacral nerve stimulation for treatment of refractory urinary urge incontinence. J Urol. 1999;162:352-357.
National Library of Medicine. National Institutes of Health (NIH). NCT00200005: Sacral nerve stimulation for anal incontinence and bowel control (MDT-301). https://clinicaltrials.gov/study/NCT00200005. Accessed February 12, 2026.