Research areas of interest

Acute care and monitoring

Digital health

• Clinical, economic, and workflow outcomes with implementation of HealthCast^TM Vital Sync^TM remote monitoring in the recovery space
• Clinical, economic, and workflow outcomes using the Vital Sync^TM Ventilation Dashboard application
• Pre-hospital use of the Corsano^TM* multi-parameter wearable to monitor patients pre-surgery and improve patient outcomes
• Clinical, economic, and workflow outcomes of in-hospital Corsano^TM* multi-parameter wearable implementation post-surgery
• Use of Corsano^TM* multi-parameter wearable for hospital to home or hospital at home monitoring post-surgery

Respiratory

• Performance of Nellcor^TM pulse oximetry monitoring system vs other pulse oximeters in acute and critical care settings
• Clinical use of Nellcor^TM pulse oximetry with Nell-EQ^TM intelligent processor
• Nellcor^TM pulse oximetry use in challenging conditions (i.e. low perfusion, cardiac abnormalities, dark skin pigmentation) in the NICU/PICU/L&D and acute care (OR, ICU, ER)
• Nellcor^TM pulse oximetry performance in the CVICU
• Performance of Microstream^TM capnography vs other capnography filterlines in procedural sedation, critical care, and recovery settings
• Impact of Microstream^TM capnography during moderate to deep sedation on clinical, economic, and clinician workflow outcomes
• Clinical, economic, and clinician workflow improvements using Smart Capnography^TM algorithms during patient recovery
• Improved secretion management as part of a VAP bundle using Shiley^TM flexible evac oral endotracheal or tracheostomy tube with TaperGuard^TM cuff
• Clinical and economic outcomes with Shiley^TM pediatric oral/nasal endotracheal tube with TaperGuard^TM cuff
• Performance of Shiley^TM endotracheal or tracheostomy tubes vs other endotracheal/ tracheostomy tubes
• Clinical outcomes associated with use of the DAR^TM closed suction system with patient access valve
• Protection of patients and clinicians with DAR^TM filters or DAR^TM filter HME
• Reduced cuff pressure variance or improved clinical outcomes and clinician workflow using the Puritan Bennett^TM cuff pressure manager
• Combined use of the Puritan Bennett^TM cuff pressure manager with Shiley^TM endotracheal or tracheostomy tubes and accessories

Perioperative

• BIST^TM brain monitoring system-guided anesthesia and incidence of burst suppression and perioperative neurocognitive dysfunction
• Clinical and economic outcomes with combined use of BIS^TM technology and raw EEG/DSA
• Performance of BIS^TM quatro sensor vs generic pEEG sensors with the BIS^TM brain monitoring system
• Environmental impact of reducing anesthetic use (volatile gases and TIVA) with BIS^TM technology
• Incidence and impact of cerebral or somatic desaturation, and improved clinical and economic outcomes using the INVOS^TM regional oximetry system in the OR and ICU
• Use of INVOS^TM regional oximetry with other hemodynamic monitoring parameters
• Multimodal brain monitoring using both INVOS^TM regional oximetry and BIS^TM brain monitoring systems
• Clinical and economic performance of McGRATH^TM MAC video laryngoscope or McGRATH^TM MAC+ video laryngoscope vs direct laryngoscopy or other video laryngoscopy
• Environmental impact and sustainability of McGRATH^TM MAC or McGRATH^TM MAC+ video laryngoscope
• Pediatric use of size 1 McGRATH^TM MAC disposable laryngoscope blade
• Clinical outcomes using McGRATH^TM MAC X3 blade (hyperangulated)

Brain

DBS Movement Disorders

• Neural sensing and anatomical insights to inform DBS programming workflows and therapy management.
• Exploration of neural biomarkers across approved movement disorder indications
• Clinical research on sensing-enabled DBS approaches in Parkinson’s disease, essential tremor, and dystonia.
• Use of digital and remote data tools to expand access, improve practice efficiency support reduced longitudinal patient management burden.

DBS Epilepsy

• Thalamic neural activity to inform DBS programming workflows and therapy management.
• Sensing-enabled DBS approaches leveraging existing device capabilities.
• DBS therapy approaches across epilepsy subtypes, including generalized epilepsies and expanded thalamic targets, in adult and pediatric populations.
• Use of digital and remote data tools to support clinical decision-making.

LITT (Visualase)

• Clinical research evaluating laser interstitial thermal therapy in brain tumors.
• Biological effects of LITT, including blood–brain barrier modulation and interaction with adjunctive therapies.
• Evidence generation supporting regional access and reimbursement considerations.

Ear, nose, and throat (ENT)

Parathyroid Detection

• Assessing the impact of preventing hypoparathyroidism, including potential effects on patient quality of life and healthcare costs.
• Evaluating healthcare resource utilization, including surgical time, cost effectiveness, and overall cost of care.
• Assessment of parathyroid gland vascularity, reimplantation, including evaluation of patient quality of life and healthcare resource utilization.

Drug Eluting Stents

• Controlled studies, especially outside the US.
• PROPEL^TM sinus implant use with nasal packing.

Nerve Monitoring

• Otology procedures including active facial nerve monitoring.
• Head and Neck procedures using NIM NerveTrend^TM technology or NIM Nerveassure^TM technology.
  

Novapak^TM

• Studies evaluating longer-term clinical outcomes and follow-up data.
  

ApexCut^TM

• Generation of cost, efficiency, and clinical outcome data for these blades, including comparative evaluations against alternative technologies and existing surgical approaches.

Interventional Cardiology Technologies

Proposals should address new ideas, gaps in knowledge, and generate valuable insights into clinical outcomes, health economics, or patient-centered outcomes. All research proposals will be evaluated based on scientific merit, alignment with Medtronic’s business strategy, and potential impact on clinical practice.

Coronary

Medtronic invites physician-initiated research proposals that advance PCI using our coronary technologies; we are interested in proposals in the following areas:

• Real-world outcomes in complex PCI or high-risk populations treated with Medtronic coronary products
• Studies evaluating Prevail™ DCB in patients with de novo coronary artery disease
• Application of CathWorks FFRangio™ to optimize PCI decision-making and treatment strategies in the cath lab
• Novel uses of Medtronic coronary products to improve clinical outcomes, resource utilization, or quality of life
  

Renal denervation

• Medtronic is committed to advancing the science and clinical practice of renal denervation (RDN) for hypertension and related conditions. We welcome investigator-initiated research proposals that align with the following broad areas of interest:
• Improve understanding of which patients benefit most from RDN
• Explore new clinical applications and broader outcomes for RDN
• Advance innovation and optimization in RDN therapy

Neurovascular

• Real world evidence on chronic sub-dural Hematomas, Artisse, and Flow diversion
• Emerging Indications

Please reach out to rs.nvoma@medtronic.com with further questions on these topics or Neurovascular ISRs. 

Pain Interventions

Spinal Cord Stimulation (SCS)

• Clinical research on closed loop SCS therapy in approved indications
• Exploration of objective and composite measures of patient therapy experience
•  Use of digital and remote data tools to expand access, improve practice efficiency or support reduced longitudinal patient management burden
• Automated programming workflows and next-generation algorithms
• Indication expansion for novel populations with significant needs
• Functional restoration & mechanism of action

Intrathecal Pump Delivery (TDD)

• Long-term durability, safety, and cost-effectiveness
• Workflow guidance on programming and dose titration for specific populations
• Procedural guidance, including catheter placement
• Advanced analytics on subpopulations, including abdominal pain, pelvic pain, malignant pain, and spasticity

Interventional Therapies (BVNA, VCF, OsteoCool, Emprint)

• Healthcare utilization and cost effectiveness
• Expanded indications for OsteoCool and Emprint
• Enhanced patient selection utilizing real-world evidence and pre-existing data
• Novel procedural advancements and/or enhancements

Pelvic health

Sacral Neuromodulation

• Expand access, improve efficacy, and simplify SNM

Tibial Neuromodulation

• Expand access, explore stimulation parameters, and improve efficacy

Digital Health

• Increase utilization of digital tools to expand access, improve practice efficiency, or reduce post implant management