Microwave ablation generators

Emprint™ HP ablation generator with Thermosphere™ technology

Emprint™ ablation system cartEmprint™ ablation system cart
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Microwave ablation generators

Emprint™ HP ablation generator with Thermosphere™ technology

The Emprint™ HP ablation generator uses patented Thermosphere™ technology to treat nonresectable liver tumors.

Description

The Emprint™ HP ablation generator gives you more volume with a single antenna.

Using our patented Thermosphere™ technology, the Emprint™ HP ablation generator enables a minimally invasive procedure with:​

  • Large ablations, with up to 40% more volume compared to the original Emprint™ ablation system1​
  • Proven spherical shape,2–8 giving you flexibility in antenna placement approach9
  • Consistent ablative margins greater than 5 mm†​,9
  • Scalability, allowing you to create both small and large ablation zones1

Features

The Emprint™ HP ablation system supports your journey from careful planning to predictable success when treating nonresectable liver tumors. It enables a minimally invasive procedure with:

High accuracy10

Arrow target

Predictable margins9

Graphs

Expand your treatment options.11

Our patented Thermosphere™ technology can help lower the chance of recurrence by achieving large ablation volumes with predictable margins.7

The Emprint™ HP ablation procedure can be combined with additional therapies, like resection or chemotherapy, to give your patients a more comprehensive treatment.11

Compared to surgical resection, our purpose-built innovation helps you eradicate your patients’ tumors and preserve more of their healthy parenchyma7,12 — because their future depends on both. Take less healthy liver, give them more life.


Clinical results may vary. Not all patients’ results are the same.

Emprint™ HP ablation generator with Thermosphere™ technology​

Emprint™ zone chart app

The Emprint™ ablation zone mobile application puts the ablation setting details you need in the palm of your hand. Comprehensive ex vivo and in vivo ablation zone reference values are included.

Available for both Android and iPhone users.

Emprint™ HP ablation zone app on a smart phone

Emprint™ ablation system with Thermosphere™ technology

The Emprint™ ablation system enables a minimally invasive procedure with high accuracy10 and predictable margins.‡,9

 

Emprint™ ablation system

Emprint™ percutaneous antennas with Thermosphere™ technology​

Both the Emprint™ and Emprint™ HP ablation generators are compatible with the Emprint™ percutaneous ablation antenna. Our patented Thermosphere™ technology creates a predictable ablation zone focused at the end of the antenna, despite varying tissue conditions.8

They are available in three lengths: short (15 cm), standard (20 cm), and long (30 cm).

Emprint™ percutaneous antennas with Thermosphere™ technology​

Clinical evidence

Multi-institutional analysis of outcomes for Thermosphere™ microwave ablation treatment of colorectal liver metastases: 
the SMAC study 

Conclusion: Thermosphere™ microwave ablation (T-MWA) is a safe and effective treatment for colorectal liver metastases (CLM) with no biliary complications reported in more than 200 ablated lesions. Local tumor progression-free survival (LTPFS) is affected by lesion size at ablation, number of lesions, minimal ablation margin, and intra-segment progression. Chemotherapy before ablation (CBA) modifies kinetics growth of the lesions but deteriorates ablation margins and does not significantly impact local tumor progression-free survival. 


Authors: Francesco De Cobelli et al 
Published by: Eur Radiol, 2022

Emprint™ ablation system: clinically relevant ablative margin

Evaluation of microwave ablation of liver malignancy with enabled constant spatial energy control to achieve a predictable spherical ablation zone

Study design: A single-center, retrospective cohort study comparing 48 subjects with hepatic tumors (total 56 tumors) treated with Emprint™ ablation system with Thermosphere™ technology to subjects who underwent conventional high-frequency MWA (n=20) or low-frequency MWA (n=20)


Authors: Thomas J. Vogl et al
Published by: Int. Journal of Hyperthermia, 2018

Ordering information

Item number Description Length (cm) Units per box
CARTHP Emprint™ HP ablation cart  —  1
CAGENHP Emprint™ HP ablation generator with Thermosphere™ technology  —  1
CAPUMP1 Emprint™ ablation pump  —  1
CA190RC1 Emprint™ ablation reusable cable 190 1
RFASW Emprint™ footswitch  —  1
RTP20 Emprint™ remote temperature probe 20 1
CA15L2 Emprint™ short percutaneous antenna with Thermosphere™ technology 15 1
CA20L2 Emprint™ standard percutaneous antenna with Thermosphere™ technology 20 1
CA30L2 Emprint™ long percutaneous antenna with Thermosphere™ technology 30 1

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Independent study was performed using the 100 W Emprint ablation generator. A total of 56 tumors ablated with the Emprint ablation system had a median size of 1.4 cm (range 0.4 to 3.7 cm).

Compared to surgical resection.


  1. Based on internal testing report RE00205202, Emprint™ performance report, versus the Emprint™ ablation generator. January 2020.
  2. Imajo K, Tomeno W, Kanezaki M, et al. New microwave ablation system for unresectable liver tumors that forms large, spherical ablation zones. J Gastroenterol Hepatol. 2018;33(12):2007–2014.
  3. Zaidi N, Okoh A, Yigitbas H, Yazici P, Ali N, Berber E. Laparoscopic microwave thermosphere ablation of malignant liver tumors: an analysis of 53 cases. J Surg Oncol. 2016;113(2):130–134.
  4. Based on internal testing report R0043973, In vivo performance testing of the Emprint™ microwave ablation system in a porcine model. March 2014.
  5. Based on internal testing report R0054596, Emprint™ MWA system with CT imaging in a porcine model. April 2016.
  6. Howk K L C, Peterson D, Cafaro A. Consistent and predictable spherical ablation shape in both liver and lung: performance of the Emprint™ ablation system with Thermosphere™ technology in an in vivo porcine model. Poster 129. Journal of Vascular. 2015.
  7. Lerardi AM, Mangano A, Floridi C, et al. A new system of microwave ablation at 2450 MHz: preliminary experience. Updates Surg. 2015;67(1):39–45.
  8. De Cobelli F, Marra P, Ratti F, et al. Microwave ablation of liver malignancies: comparison of effects and early outcomes of percutaneous and intraoperative approaches with different liver conditions. Med Oncol. 2017;34(4):49.
  9. Vogl TJ, Basten LM, Nour-Eldin A, et al. Evaluation of microwave ablation of liver malignancy with enabled constant spatial energy control to achieve a predictable spherical ablation zone. Int J Hyperthermia. 2018;34(4):492–500.

  1. De Cobelli F, Marra P, Ratti F, et al. Microwave ablation of liver malignancies: comparison of effects and early outcomes of percutaneous and intraoperative approaches with different liver conditions. Med Oncol. 2017;34(4):49.
  2. Park MJ, Kim YS, Rhim H, Lim HK, Lee MW, Choi D. A comparison of US-guided percutaneous radiofrequency ablation of medium-sized hepatocellular carcinoma with a cluster electrode or a single electrode with a multiple overlapping ablation technique. J Vasc Interv Radiol. 2011;22(6):771–779.
  3. Bruix J, Reig M, Sherman M. Evidence-based diagnosis, staging, and treatment of patients with hepatocellular carcinoma. Gastroenterology. 2016;150(4):835–853.