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Synthetic bone graft, which is artificially produced, bulks up or extends the supply of available autograft bone (bone harvested from your own body). There are many extender biomaterials and tissues available, and their properties depend heavily on their origin and how they are processed.
Synthetics work through a process called osteoconduction. Imagine a vine growing through and around a trellis. Synthetic bone graft works in a similar fashion. It is like a scaffold (trellis) that supports the bone-forming cells (the vine) as they grow new bone over time.
Mastergraft™ products are composed of bovine (cow) collagen and/or a synthetic calcium phosphate material that is similar to the mineral component of natural bone. They come in various shapes and sizes, and they serve as passive scaffolds to which your body’s own bone-forming cells attach for the formation of new bone. These products are intended to be used in combination with your own bone (autograft) in the surgical site, to reduce or eliminate the need to take additional autograft from your hip.
This product is not intended to provide structural support during the healing process; therefore, Mastergraft is contraindicated where the device is intended as structural support in the skeletal system. Conditions representing relative contraindications include:
Mastergraft Strip, Mastergraft EXT, and Mastergraft Putty should not be used in patients with a known history of hypersensitivity to bovine derived materials.
A listing of potential adverse events includes, but is not limited to:
For more details see Important Safety Information.