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About the Medtronic Symplicity™ Procedure

  

BLOOD PRESSURE PROCEDURE

About the procedure

Move beyond the barriers of high blood pressure (hypertension) with the renal denervation blood pressure procedure, which offers a single, minimally invasive approach.

  

  

Illustration showing a cellphone held in a hand with a blood pressure reading on the screen

  

What makes the procedure different from traditional management options?

  • Proven safe and effective*1–3
  • Keeps working 24 hours a day — like a pill you never have to remember to take2,3

Adverse events include, but are not limited to, bruising and pain. Results may vary.

↓ 16.7

mmHg

In a three-year study of people who received the procedure, it helped reduce BP by 16.7 mmHg.*1

Explore the science.

Learn more about how the renal denervation blood pressure procedure can help get your numbers down.*1–3

See how it works

Beyond basic management for high blood pressure

See what happens during the renal denervation blood pressure procedure.

Get the details

Set your expectations.

Important information about the benefits and risks of the renal denervation blood pressure procedure

See benefits and risks

Another way to lower your blood pressure

Find out what to expect during the day of your renal denervation blood pressure procedure.

Plan your day

Find more answers.

Dive into our FAQ about the renal denervation blood pressure procedure.

Read FAQ

Always follow the instructions specified by your doctor or the nursing staff. Always follow the discharge instructions provided by your physician after your procedure.

References

1

Mahfoud F, Mancia G, Schmieder R, et al. Blood pressure and MACE reductions after renal denervation: 3-year Global Symplicity Registry results. Presented at PCR e-course 2022.

2

Kandzari DE, Böhm M, Mahfoud F, et al. Effect of renal denervation on blood pressure in the presence of antihypertensive drugs: 6-month efficacy and safety results from the SPYRAL HTN-ON MED proof-of-concept randomised trial. Lancet. June 9, 2018;391(10137):2346–2355.

3

Böhm M, Kario K, Kandzari DE, et al. Efficacy of catheter-based renal denervation in the absence of antihypertensive medications (SPYRAL HTN-OFF MED Pivotal): a multicentre, randomised, sham-controlled trial. Lancet. May 2, 2020;395(10234):1444–1451.