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The Avalus bioprosthesis is a pericardial aortic surgical valve designed for better overall performance, improved implant experience, and a contemporary design to facilitate future valve-in-valve (ViV).
Download Product BrochureOur Avalus valve is the next-generation stented pericardial aortic valve — a powerful synergy of over 40 years of industry experience and proven valve design — for excellent implantability for you and performance for your patients.
Read about the clinical success of the Avalus.
Interior-mounted leaflets minimize damaging contact with the frame — a design platform for long-term durability.
AOA™ tissue treatment* to mitigate calcification — over 20 years of clinical use in the Medtronic surgical tissue valve portfolio.1,2
Designed to achieve 100% coaptation and minimize central regurgitation.
Flexible support frame with firm base designed to maintain circularity and consistent hemodynamic performance.
Avalus |
Valve Size (mm) |
Stent Diameter (TAD†) (mm) |
Internal Orifice Diameter‡ (mm) |
External Sewing Ring Diameter (mm) |
Valve Profile Height (mm) |
Aortic Protrusion (mm) |
|
---|---|---|---|---|---|---|---|
|
|
(1) |
(2) |
(2a) |
(3) |
(4) |
(5) |
40019 |
19 |
19 |
17.5 |
18 |
27.0 |
13.0 |
11.0 |
40021 |
21 |
21 |
19.5 |
20 |
29.0 |
14.0 |
12.0 |
40023 |
23 |
23 |
21.5 |
22 |
31.0 |
15.0 |
13.0 |
40025 |
25 |
25 |
23.5 |
24 |
33.0 |
16.0 |
14.0 |
40027 |
27 |
27 |
25.5 |
26 |
36.0 |
17.0 |
15.0 |
Order Number |
Description |
---|---|
7420 |
Valve Handle |
7400S |
Avalus Sizers |
T7400 |
Tray, Accessory, Avalus |
Training, education, and collaboration on the treatment of mitral and tricuspid valve disease.
Register HereNo clinical data is available which evaluates the long-term impact of AOA treatment in patients.
TAD — tissue annulus diameter.
Measurement shows stent frame including tissue (2) and stent frame excluding tissue (2a).
Tadokoro N, Fukushima S, Shimahara Y, et al. Comparison of safety and haemodynamic performance between the Avalus™ stented aortic valve bioprosthesis and Magna™ valve in Japanese patients. Gen Thorac Cardiovasc Surg. July 2021;69(7):1060-1069.
The latest results of the Perigon Study, presented by Prof. Dr. Robert J.M. Klautz during EACTS 2021. The PERIGON Pivotal Trial regarding the Avalus valve is a prospective, interventional, nonrandomized, worldwide, multi-site trial, with each center following a common protocol. The study was designed in accordance with the recommendations of the EN ISO 5840:2009 standard for cardiac valve prostheses and the U.S. Food and Drug Administration (FDA) Heart Valve Guidance (2010; DRAFT) and conducted in accordance with the Declaration of Helsinki and good clinical practice guidelines. Valve-related events and deaths were adjudicated by an independent clinical events committee (CEC). All study echocardiograms were analyzed by an independent core laboratory (MedStar Health Research Institute, Washington, D.C.). Safety oversight was provided by an independent data and safety monitoring board (DSMB). This trial is registered at www.clinicaltrials.gov, NCT02088554.
Medtronic Freestyle™ aortic root bioprosthesis was first implanted clinically in August 1992. Freestyle Aortic Root Bioprosthesis 15-Year Clinical Compendium. © 2016 Medtronic.
Ruzicka DJ, Hettich I, Hutter A, et al. The complete supraannular concept: in vivo hemodynamics of bovine and porcine aortic bioprostheses. Circulation. September 15, 2009;120(11 Suppl):S139-145.