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cardiac ablation and mapping
Designed for pulmonary vein isolation (PVI), the Medtronic cryoballoon ablation system offers an anatomical approach to addressing atrial arrhythmias, creating wide antral, contiguous circumferential lesions surrounding the target anatomy.
The Arctic Front™ cryoablation system is the leader in cryoballoon technology with over 16 years of clinical experience, treating more than one million patients worldwide.1
The Arctic Front™ family of cryoballoons enables safe, effective, and efficient procedures. The Arctic Front™ system provides physicians with a straightforward approach to PVI with minimal applications, durable lesions, and delivering consistent and predictable results,2 for first-line, paroxysmal, and persistent AF patients.3-6
The Medtronic cryoablation system includes the Freezor™ family of cryoablation catheters, which include devices approved for the treatment of AF or pediatric and adult AVNRT.7,8
The Medtronic Arctic Front™ cryoballoon system is the only ablation system FDA-approved as an initial rhythm control strategy for patients with paroxysmal atrial fibrillation. It is also indicated for the treatment of paroxysmal and persistent* AF patients.
Meta-analysis of three randomized first-line trials, STOP AF First, EARLY-AF, and Cryo-FIRST, demonstrates cryoablation is more effective than antiarrhythmic drugs as an initial first-line therapy for patients with paroxysmal AF.14
Access detailed product information, including spec sheets, videos, and presentations.
Indicated for symptomatic persistent AF defined as a continuous, sustained episode lasting longer than 7 days but ≤ 6 months.
Providencia R, Defaye P, Lambiase PD, et al. Results from a multicentre comparison of cryoballoon vs. radiofrequency ablation for paroxysmal atrial fibrillation: Is cryoablation more reproducible? Europace. 2017;19(1):48–57.
Fry D. Medtronic Cryoballoon Adoption. Medtronic data on file. February 2020.
Packer DL, Kowal RC, Wheelan KR, et al. Cryoballoon ablation of pulmonary veins for paroxysmal atrial fibrillation: first results of the North American Arctic Front (STOP AF) pivotal trial. J Am Coll Cardiol. 2013;61(16):1713–1723.
Su WW, Reddy VY, Bhasin K, et al. Cryoballoon ablation of pulmonary veins for persistent atrial fibrillation: Results from the multicenter STOP Persistent AF trial. Heart Rhythm. 2020;17(11):1841–1847.
Wazni OM, Dandamudi G, Sood N, et al. Cryoballoon ablation as initial therapy for atrial fibrillation. N Engl J Med. 2021;384(4):316–324.
Wazni OM, Dandamudi G, Sood N, et al. Cryoablation versus antiarrhythmic drug therapy as initial treatment for atrial fibrillation: impact on quality of life. J Am Coll Cardiol. 2021;77(18_Supplement_1):225–225.
Wells P, Dubuc M, Klein GJ, et al. Intracardiac ablation for atrioventricular nodal reentry tachycardia using a 6 mm distal electrode cryoablation catheter: Prospective, multicenter, North American study (ICY-AVNRT STUDY). J Cardiovasc Electrophysiol. 2018;29(1):167–176.
Avari JN, Jay KS, Rhee EK, et al. Experience and results during transition from radiofrequency ablation to cryoablation for treatment of pediatric atrioventricular nodal reentrant tachycardia. Pacing Clin Electrophysiol. 2008;31(4):454–460.
Sarabanda AV, Bunch TJ, Johnson SB, et al. Efficacy and safety of circumferential pulmonary vein isolation using a novel cryothermal balloon ablation system. J Am Coll Cardiol. 2005;46(10):1902–1912.
Khairy P, Chauvet P, Lehmann J, et al. Lower incidence of thrombus formation with cryoenergy versus radiofrequency catheter ablation. Circulation. 2003;107;(15):2045–2050.
Friedman PL. Catheter cryoablation of cardiac arrhythmias. Curr Opin Cardiol. 2005;20(1):48–54.
Knecht S, Sticherling C, Roten L, et al. Technical and procedural comparison of two different cryoballoon ablation systems in patients with atrial fibrillation. J Interv Card Electrophysiol. 2022;62(2):409–416.
Fortuni F, Casula M, Sanzo A, et al. Meta-Analysis Comparing Cryoballoon Versus Radiofrequency as First Ablation Procedure for Atrial Fibrillation. Am J Cardiol. 2020;125(8):1170–1179.
Andrade JG, Wazni OM, Kuniss M, et al. Cryoballoon Ablation as Initial Treatment for Atrial Fibrillation: JACC State-of-the-Art Review. J Am Coll Cardiol. 2021;78(9):914–930.