Patient-Ventilator Asynchrony

Up to 25% of patients with acute respiratory failure exhibit a significant proportion of asynchronous breaths (>10 %)([FOOTNOTE=Robinson BR, Blakeman TC, Toth P, Hanseman DJ, Mueller E, Branson RD. Patient-ventilator asynchrony in a traumatically injured population. Respiratory care. 2013;58(11):1847-1855.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=1203233])

Exhibiting a significant proportion of asynchronous breaths is associated with an almost five-fold increase in ICU mortality,¹ a three-fold increase in median duration of mechanical ventilation and a greater than two-fold increase in median hospital length of stay.²

Patient-ventilator asynchrony consists of multiple types of asynchrony. The identification and treatment of each type is multifactorial, influenced by a myriad of ventilator-related and patient-specific factors.([FOOTNOTE=Pierson DJ. Patient-ventilator interaction. Respiratory care. 2011;56(2):214-228.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=1203232])

Features included in the Puritan Bennett™ 980 ventilator may help improve patient synchrony by better aligning triggering, flow, breath delivery, and cycling with individualized patient need, promoting more natural breathing compared to conventional mechanical ventilation.([FOOTNOTE=Xirouchaki N, Kondili E, Vaporidi K, et al. Proportional assist ventilation with load-adjustable gain factors in critically ill patients: comparison with pressure support. Intensive care medicine. 2008;34(11):2026-2034.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=719462 ])