We are excited to welcome the CathWorks FFRangio™ system to our portfolio.

This milestone represents the culmination of a four-year partnership. We are excited to welcome the CathWorks team and their expertise as we push the boundaries of coronary physiology.

The new standard in coronary physiology.1

Wire-free, drug-free, multivessel physiology

The CathWorks FFRangio™ system uses a wire-free, drug-free approach to convert routine angiograms into a map of the entire coronary tree, with FFRangio values at every point.

Optimizes clinical decision-making1

The CathWorks FFRangio™ system equips physicians with deep insights to make critical, patient-focused decisions. Built-in tools support planning and optimizing the treatment of coronary artery disease (CAD).†,1

View an image of the CathWorks FFRangio™ system monitor showing pullback curve, lesion impact, and the sizing tool with numbered callouts for each.

Pullback curve

Plan: the pullback curve differentiates functional patterns of CAD to target critical segments.

View an image of the CathWorks FFRangio™ system monitor showing pullback curve, lesion impact, and the sizing tool with numbered callouts for each.

Sizing tool

Optimize: the sizing tool accurately measures2 lesion dimensions and co-registers on the angiograms for an alternate view.

Unmatched outcomes1

The ALL-RISE trial data adds to the robust clinical evidence supporting the CathWorks FFRangio™ system1,3–5 and promotes the use of coronary physiology in assessing and treating CAD.

  • Demonstrating a one-year MACE‡ rate noninferior to wire-based physiology in the ALL‑RISE trial1
  • Providing statistically significant improvement in resource utilization and reduced procedure time1
Download ALL-RISE summary (open in new window)
Explore ALL-RISE full publication (open in new window)

Updates from EuroPCR 2026: introduction to LAD sub-analysis 

ALL-RISE sub-analysis of the critical LAD vessel reinforces the results observed with the CathWorks FFRangio system, showing a trend toward lower MACE and statistically significant improvements in resource utilization and procedure time compared to wire-based physiology.1,6,7


59%

ALL-RISE patients had the LAD assessed6

 

 

  • 59% of ALL-RISE patients had the LAD assessed6 
  • CathWorks FFRangio system demonstrated a trend toward lower 1-year MACE for LAD lesions versus wire-based physiology (5.2% vs. 8.3%, p=0.065) 
  • Statistically significant reduction of approximately 70% in myocardial infarction for LAD lesions assessed by FFRangio ( 1. 1 % vs. 3.6%, p=0.008)
  • 99% physiologic assessment success rate in LAD lesions with the CathWorks FFRangio system


Significant improvements in resource utilization and procedure efficiency in LAD lesions, including: 

  • 22% lower physiology analysis time and 19% lower procedure time. 
  • 31% lower fluoroscopy time and 19% lower contrast volume.

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