Enveloppe antibactérienne absorbable Think TYRX™

Enveloppe antibactérienne absorbable Think TYRX™

L’enveloppe antibactérienne absorbable TYRXMC est conçue pour être utilisée avec les dispositifs électroniques cardiaques implantables (DÉCI), y compris les défibrillateurs automatiques implantables (DAI) et les stimulateurs cardiaques.

The overall haematoma rate was 2.22% at 30 days, and there was no difference between treatment groups (p = 0.39).

All major CIED infections in patients with haematoma were pocket infections, none were due to bacteremia or endocarditis. 

Brief Statement:

TYRX™ Cardiac Absorbable Antibacterial Envelope

See the device manual for detailed information regarding the instructions for use, indications, contraindications, warnings, precautions, and potential adverse events. If using an MRI SureScanTM device, see the MRI SureScanTM technical manual before performing an MRI. For further information, contact your local Medtronic representative and/or consult the Medtronic website at medtronic.eu

The envelope is intended to hold the following CIED securely to create a stable environment when implanted in the body at the following locations: Implantable Pulse Generator (IPG), Implantable Cardioverter Defibrillator (ICD) and Cardiac Resynchronization Therapy Devices (CRT-P and CRT-D); implant locations are pectoral, abdominal, or flank (lateral to the body midline and superior to the gluteal) regions.

The envelope contains the ancillary medicinal substances rifampicin and minocycline, which have been shown to reduce infection in an in vivo model of bacterial challenge following surgical implantation of the device.

The envelope is contraindicated for use in patients with allergy or history of allergy to tetracyclines, rifampicin, or absorbable sutures; in patients with systemic lupus erythematosus (SLE) because minocycline has been reported to aggravate this condition; in contaminated or infected wounds.