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Patients & Caregivers

This information is designed to provide you with helpful educational information but is for information purposes only, is not medical advice, and should not be used as an alternative to speaking with your doctor. No representation is made that the information provided is current, complete, or accurate. Medtronic does not assume any responsibility for persons relying on the information provided. Be sure to discuss questions specific to your health and treatments with a healthcare professional. For more information please speak to your healthcare professional.

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Home Patients & Caregivers Conditions Digestive and Gastrointestinal Conditions About Inflammatory Bowel Disease Inflammatory Bowel Disease - Symptoms and Causes

Digestive and Gastrointestinal Conditions (opens new window)
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  • About Inflammatory Bowel Disease
    • Inflammatory Bowel Disease - Symptoms and Causes
    • Living with Inflammatory Bowel Disease – Know the Symptoms
    • Diagnostic and Treatment Options – Inflammatory Bowel Disease
    • Inflammatory Bowel Disease – Frequently Asked Questions
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ABOUT THE CONDITION

What is Inflammatory Bowel Disease

Inflammatory Bowel Disease is caused by chronic inflammation of the intestinal tract. There are two forms of Inflammatory Bowel Disease: Crohn’s Disease and Ulcerative Colitis.

Crohn's Disease and Ulcerative Colitis are similar — so similar that they're often mistaken for one another. Both diseases cause inflammation of the lining of your digestive tract, and both may result in severe bouts of diarrhoea and abdominal pain.2

Crohn's disease can occur anywhere in your digestive tract, often spreading deep into the layers of affected tissues.

Ulcerative Colitis, on the other hand, usually affects only the innermost lining of your large intestine (colon) and rectum.

Inflammatory Bowel Disease Symptoms

  • Abdominal pain
  • Nausea and vomiting
  • Weight loss or weight gain
  • Various associated complaints or diseases, often autoimmune disorders (arthritis, skin lesions, and liver and bile duct disorders)
  • Diarrhoea and bloody stool: Food moving through your digestive tract can cause inflamed tissue to bleed, ranging from bright red blood or darker blood mixed with your stool or in the toilet bowl. 
Treatment options
Causes

Crohn’s Disease-specific symptoms 

Inflammation causes cells in the affected areas of your intestine to secrete large amounts of water and salt. Because the colon can't absorb this excess fluid, you develop diarrhea. Altered intestinal contractions also can contribute to loose stools. Diarrhoea can range from mild to severe.3

Ulcerative Colitis-specific symptoms 

Diarrhoea can also be a symptom of Ulcerative Colitis. However, patients with ulcerative colitis tend to experience bloody diarrhoea and also something called tenesmus. Tenesmus is the sensation of having to move one's bowels.4

Causes of Inflammatory Bowel Disease 

The exact cause of Inflammatory Bowel Disease remains unknown. One possible cause is an immune system malfunction. When your immune system tries to fight off an invading virus or bacterium, an atypical immune response causes the immune system to also attack the cells in the digestive tract.1

Treatment options
Causes

Inflammatory Bowel Disease Diagnostic and Treatment Options

Usually, treatment of Inflammatory Bowel Disease begins with medical therapy and there are also several surgical options your doctor may discuss with you.

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Living with Inflammatory Bowel Disease

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Diagnostic and Treatment Options

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FAQ's

Frequently Asked Questions


  1. Mayo Clinic https://www.mayoclinic.org/diseases-conditions/inflammatory-bowel-disease/symptoms-causes/syc-20353315
  2. Crohn’s & Ulcerative Colitis: Know the Difference? April 2023. Available at: https://www.webmd.com/ibd-crohns-disease/crohns-colitis-difference
  3. Pathophysiology of IBD associated diarrhea. Arivarasu N. Anbazhagan et al. May 2018. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179131/#:~:text=The%20pathogenesis%20of%20IBD%2Dassociated,pathogens%20to%20the%20intestinal%20mucosa
  4. Tenesmus: The Troubling Symptom You Can’t Ignore. H Lindsay, Nov 2023. https://www.everydayhealth.com/ulcerative-colitis/symptoms/tenesmus-troubling-symptom-you-cant-ignore/ 
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