Overview

Transorb™ self-gripping resorbable mesh for open extraperitoneal ventral hernia repair

Transorb™ mesh is designed to provide the robust reinforcement your patients need throughout the critical healing period — and then fully resorb.2,6

Superior strength†,1,2
  • Stronger mesh: a significantly higher tensile strength than competitor mesh‡,1
  • Stronger attachment: attachment force to the tissue is 1.6 times stronger§,◊,2 with ProGrip™ technology
  • Stronger repair: macroporosity allows for excellent tissue ingrowth, providing mechanical strength to the defect repair◊,2–5
Repairs. Reinforces. Resorbs.◊,2–6
  • Tissue integration: resorbable microgrips support excellent tissue integration◊,2,7
  • Critical healing period: provides the same support as a permanent synthetic mesh during the critical healing period, while gradually resorbing into the body over time◊,¶,2,6
  • Pore size matters: large pores are associated with a reduced risk of infection and shrinkage,2,3,8 as well as reduced seroma formation◊,2,9

Order Information

ORDER CODE DESCRIPTION DIMENSIONS QUANTITY
TSB1510 Transorb™ self-gripping resorbable mesh, poly-L-lactide, poly-trimethylene carbonate (PLLA/TMC) copolymers with grips on one side 15 cm × 10 cm
(5.9 in × 3.9 in)
1 per box
TSB2020 Transorb™ self-gripping resorbable mesh, poly-L-lactide, poly-trimethylene carbonate (PLLA/TMC) copolymers with grips on one side 20 cm × 20 cm
(7.9 in × 7.9 in)
1 per box
TSB3030 Transorb™ self-gripping resorbable mesh, poly-L-lactide, poly-trimethylene carbonate (PLLA/TMC) copolymers with grips on one side 30 cm × 30 cm
(11.8 in × 11.8 in)
1 per box
TSB4030 Transorb™ self-gripping resorbable mesh, poly-L-lactide, poly-trimethylene carbonate (PLLA/TMC) copolymers with grips on one side 40 cm × 30 cm
(15.7 in × 11.8 in)
1 per box

Order Information

ORDER CODE DESCRIPTION DIMENSIONS QUANTITY
TSB1510 Transorb™ self-gripping resorbable mesh, poly-L-lactide, poly-trimethylene carbonate (PLLA/TMC) copolymers with grips on one side 15 cm × 10 cm
(5.9 in × 3.9 in)
1 per box
TSB2020 Transorb™ self-gripping resorbable mesh, poly-L-lactide, poly-trimethylene carbonate (PLLA/TMC) copolymers with grips on one side 20 cm × 20 cm
(7.9 in × 7.9 in)
1 per box
TSB3030 Transorb™ self-gripping resorbable mesh, poly-L-lactide, poly-trimethylene carbonate (PLLA/TMC) copolymers with grips on one side 30 cm × 30 cm
(11.8 in × 11.8 in)
1 per box
TSB4030 Transorb™ self-gripping resorbable mesh, poly-L-lactide, poly-trimethylene carbonate (PLLA/TMC) copolymers with grips on one side 40 cm × 30 cm
(15.7 in × 11.8 in)
1 per box

Specifications

Materials Poly-L-lactide, poly-trimethylene carbonate copolymer (PLLA/TMC) with grips on one side10
Resorption Mesh degradation by hydrolysis is nearly complete in 18–24 months, with remaining fibers essentially resorbed in 36–60 months. The total resorption period depends on numerous factors, including unique patient physiology.◊,2,6
Pore size Large pore
(1.4 mm × 1.4 mm)#,2
ProGrip™ technology Grips are present over the entire mesh surface to help maintain the device in place during abdominal wall closure11,12 and may limit the need for additional fixation◊,13

Frequently asked questions

What are the indications for use?
Transorb™ self-gripping resorbable mesh is intended to be used for the reinforcement of abdominal wall soft tissues where weakness exists in open procedures involving ventral hernia repair.

Where is Transorb™ mesh designed to be used?
Transorb™ self-gripping resorbable mesh is designed for ventral hernia repair when placed in an extraperitoneal space by open surgical approach.

How long does Transorb™ mesh take to resorb?
At eighteen to twenty four months, mesh degradation is nearly complete. The remaining mesh fibers are essentially resorbed in thirty six to sixty months post-implantation. The total resorption period depends on numerous factors, including unique patient physiology.◊,2,6

How long does Transorb™ mesh provide abdominal wall reinforcement?
Preclinical studies showed that the mesh maintains mechanical characteristics to reinforce the abdominal wall in vivo for at least twenty weeks and progressively resorbs.◊,¶,2,6

How long do the grips contribute to mesh fixation?
Preclinical studies showed that the grips contribute to the fixation of the mesh to surrounding tissue in vivo for at least four weeks.◊,13

What is the shelf life of Transorb™ mesh?
Three years.

 

The material on this website should not be considered the exclusive source of information, it does not replace or supersede information contained in the device manual(s).
Please note that the intended use of a product may vary depending on geographical approvals.
See the device manual(s) for detailed information regarding the intended use, the implant procedure, indications, contraindications, warnings, precautions, and potential adverse events.
For an MRI compatible device(s), consult the MRI information in the device manual(s) before performing an MRI.
If a device is eligible for eIFU usage, instructions for use can be found at Medtronic’s website manuals.medtronic.com.
Manuals can be viewed using a current version of any major internet  browser. For best results, use Adobe Acrobat® Reader with the browser.
Medtronic products placed on European markets comply with EU and UK legislation (if applicable) on medical devices.
For any further information, contact your local Medtronic representative and/or consult the Medtronic website.

  • † Compared to ProGrip™ self-gripping polyester mesh and P mesh. Compared to a flat sheet mesh with the same level of suture fixation. Based on preclinical testing and benchtop studies, not necessarily indicative of human clinical outcomes.

  • ‡ Based on benchtop studies, not necessarily indicative of human clinical outcomes.

  • § Compared to a flat sheet mesh with the same level of suture fixation.

  • ◊ Based on preclinical testing, not necessarily indicative of human clinical outcomes.

  • ¶ Compared to ProGrip™ self-gripping polyester mesh in simulated in vitro conditions at 20 weeks.

  • # These are mean values measured from one batch, which may vary slightly within and between batches depending on the testing method used.

  • 1. Based on internal report 1203CR764a, P mesh versus Transorb™ self-gripping resorbable mesh — ball burst statistical comparison. October 2021.

  • 2. Vestberg R, Lecuivre J, Radlovic A, Payet E, Bayon Y, Bouré L. A novel self-gripping long-term resorbable mesh providing temporary support for open primary ventral and incisional hernia. J Mater Sci Mater Med. 2023;34(11):59.

  • 3. Brown CN, Finch JG. Which mesh for hernia repair? Ann R Coll Surg Engl. 2010;92(4):272–278.

  • 4. Lake SP, Ray S, Zihni AM, Thompson DM Jr, Gluckstein J, Deeken CR. Pore size and pore shape — but not mesh density — alter the mechanical strength of tissue ingrowth and host tissue response to synthetic mesh materials in a porcine model of ventral hernia repair. J Mech Behav Biomed Mater. 2015;42:186–197.

  • 5. Weyhe D, Cobb W, Lecuivre J, et al. Large pore size and controlled mesh elongation are relevant predictors for mesh integration quality and low shrinkage — Systematic analysis of key parameters of meshes in a novel minipig hernia model. Int J Surg. 2015;22:46–53.

  • 6. Based on internal report 1203CR462a, Evaluation of Transorb™ self-gripping resorbable mesh and Deternia™ self-gripping resorbable mesh degradation and associated local tissue effects. November 2023.

  • 7. Based on internal report BIO111-a, Biological evaluation report: Transorb™ self-gripping resorbable mesh and Deternia™ self-gripping resorbable mesh. October 1, 2021.

  • 8. Weyhe D, Belyaev O, Müller C, et al. Improving outcomes in hernia repair by the use of light meshes — a comparison of different implant constructions based on a critical appraisal of the literature. World J Surg. 2007;31(1):234–244.

  • 9. Jin J, Schomisch S, Rosen MJ. In vitro evaluation of the permeability of prosthetic meshes as the possible cause of postoperative seroma formation. Surg Innov. 2009;16(2):129–133.

  • 10. Transorb™ self-gripping resorbable mesh instructions for use. Trévoux, France: Medtronic; 2023.

  • 11. Based on internal report 1203CR621a, Design verification activities associated with DI-261 (ex vivo gripping test without fixation). November 2020.

  • 12. Based on internal report 1203CR752a, Design validation and summative usability evaluation of Transorb™ self-gripping resorbable mesh — additional study. October 2021.

  • 13. Based on internal report 1203CR867, Evaluation and comparison of meshes fixation strengths in a porcine model at four weeks after implantation: pivotal study. November 2023.