Cardiac diagnostics and monitoring
PICTURE study
A study of Reveal™ insertable cardiac monitors (ICM) use in unexplained syncope patients
The PICTURE study1
Reveal™ ICMs guide diagnosis in 78% of patients with a recurrent syncopal event.
The PICTURE study investigated the effectiveness of Reveal™ ICMs in the diagnosis of unexplained, recurrent syncope in everyday clinical practice, and helped inform current syncope guidelines.2
Study design1
- 570 patients analyzed
- Patient eligibility: enrolled patients had recurrent unexplained syncope or pre-syncope
- Patients received a Reveal™ ICM
- Patients were followed up until the first syncopal recurrence, or for at least one year
Key findings1
570 patients enrolled
38%
of patients experienced a recurrence within one year.
218 patients
78%
of patients had a Reveal™ ICM-guided diagnosis.1
170 patients
75%
of patients were diagnosed with a cardiac cause.
128 patients
25%
of patients were confirmed to have a noncardiac issue.
42 patients
Physician specialists consulted before ICM insertion
Clinical impact1
PICTURE study found that syncope patients:
- Moved from specialist to specialist without answers
- Had a median of 13 inconclusive tests before a Reveal™ ICM was implanted
- 70% were hospitalized at least once for syncope and of that, one third experienced significant trauma
By using ICMs earlier in the care pathway, there is the potential to reduce the number of physicians patients see.
Study conclusion1
ICMs should be implanted earlier rather than later in the evaluation of unexplained syncope.
