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Cardiac diagnostics and monitoring

Clinical evidence

View clinical evidence on continuous cardiac monitoring.

Indications, Safety, and WarningsThe material on this website should not be considered the exclusive source of information, it does not replace or supersede information contained in the device manual(s).Please note that the intended use of a product may vary depending on geographical approvals.See the device manual(s) for detailed information regarding the intended use, the implant procedure, indications, contraindications, warnings, precautions, and potential adverse events.For a MRI compatible device(s), consult the MRI information in the device manual(s) before performing a MRI.If a device is eligible for eIFU usage, instructions for use can be found at Medtronic’s website manuals.medtronic.com.Manuals can be viewed using a current version of any major internet browser. For best results, use Adobe Acrobat® Reader with the browser.Medtronic products placed on European markets comply with EU and UK legislation (if applicable) on medical devices. For any further information, contact your local Medtronic representative.Medtronic medical devices marketed in Spain are in compliance with the Spanish legislation in force.

Proven technology¹

The LINQ™ family of ICMs (Reveal LINQ™ ICM and LINQ II™ ICM) has been featured in 1,000+ published clinical articles and abstracts.

Read a large, real-world cohort analysis of arrhythmia detection and therapeutic interventions in patients with insertable cardiac monitors².

See publication (open in new window)

Medtronic-sponsored clinical trials

CRYSTAL-AF study³

Read about how the CRYSTAL-AF study showed that the Reveal LINQ™ ICM is superior to standard monitoring for atrial fibrillation (AF) detection in cryptogenic stroke patients.

See CRYSTAL-AF study

STROKE AF study⁴

Review the STROKE AF study that showed that the Reveal LINQ™ ICM is superior to site-specific usual care for AF detection in large- and small-vessel stroke patients.

See STROKE AF study

PICTURE study⁵

Learn about the clinical impact of this study, which evaluated Reveal™ ICM use in patients with unexplained syncope.

See PICTURE study

REVEAL AF study⁶

Explore the results of this study, which evaluated continuous, long-term monitoring with Reveal LINQ™ ICM for patients at high risk for AF and stroke.

See REVEAL AF study

Related products

ICM publications. Medtronic data on file. 2023.
Saha SA, Rosemas S, Sarkar S, et al. A Large, Real-World Cohort Analysis of Arrhythmia Detection and Therapeutic Interventions in Patients With Insertable Cardiac Monitors and Long-Term Monitoring. J Cardiovasc Electrophysiol. 2025 Dec 17. doi: 10.1111/jce.70214. Epub ahead of print.
Sanna T, Diener HC, Passman RS, et al. Cryptogenic stroke and underlying atrial fibrillation (CRYSTAL AF). N Engl J Med. 2014;370(26):2478–2486. doi: 10.1056/NEJMoa1313600.
Bernstein RA, Kamel H, Granger CB, et al. Atrial fibrillation in patients with stroke attributed to large- or small-vessel disease: 3-year results from the STROKE AF randomized clinical trial. JAMA Neurol. 2023;80(12):1277–1283. doi: 10.1001/jamaneurol.2023.3931.
Edvardsson N, Frykman V, van Mechelen R, et al. Use of an implantable loop recorder to increase the diagnostic yield in unexplained syncope: results from the PICTURE registry. Europace. 2011;13(2):262–269. doi: 10.1093/europace/euq418.
Reiffel JA, Verma A, Kowey PR, et al. High incidence of previously unknown (“silent”) atrial fibrillation in patients at high risk for atrial fibrillation and stroke: primary results from the REVEAL AF study. Abstract presented at Heart Rhythm Society Annual Scientific Sessions. 2017.

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