ONS: A PROMISING NEW TREATMENT OPTION
For those with intractable Chronic Cluster Headache (iCCH), there is a new treatment option available: Occipital Nerve Stimulation (ONS) using the AnkerStimTM lead. ONS is a promising option for patients with iCCH and may reduce attack frequency and intensity, as well as medication use.
Historically, of iCCH patients receiving ONS therapy
Medtronic REC05633 09100 Clinical Evaluation Report. Internal analysis pooling efficacy data from 4 publications1-4 reporting on a total of 52 iCCH patients receiving ONS using predicate, non-AnkerStim™ leads.
ANKERSTIMTM: AN INNOVATIVE LEAD DESIGNED TO REDUCE COMMON COMPLICATIONS
The AnkerStimTM lead is designed to resist migration and improve comfort.
- Lead tip features a dual-prong tine for lead fixation in the subcutaneous layer. Two additional single-prong tines provide extra fixation between the two proximal electrodes. These tines are designed to resist migration and avoid the use of anchors in the occipital area that were a source of discomfort at the implant site.
- Flexible spring-coil electrodes adjust to the shape of the skull and are designed to improve comfort at the device site and lower the risk of skin erosion.
- 14G curved introducer needle adjusts to the curvature of the skull to help facilitate lead implant.
- 60 cm lead length allows for two strain relief loops along the lead trajectory intended to further resist lead dislodgement.
HOW ONS WORKS
- Leads are connected to an implanted neurostimulator via an extension.
- Electrical stimulation targets occipital nerves and may evoke the sensation of paresthesia.
- Stimulation is thought to work by interfering with pain signals and possibly restoring balance with non-functioning nerves.
- An external handheld programmer allows physicians to set and adjust patient stimulation parameters in clinic.
- Patients can adjust stimulation settings and turn their system on and off using their MyStim wireless device.
- Burns B, Watkins L, Goadsby PJ. Treatment of intractable chronic cluster headache by occipital nerve stimulation in 14 patients. Neurology. 2009;72(4):341-345.
- Fontaine D, Christophe Sol J, Raoul S, et al. Treatment of refractory chronic cluster headache by chronic occipital nerve stimulation. Cephalalgia. 2011;31(10):1101-1105.
- Magis D, Gerardy P-Y, Remacle J-M, Schoenen J. Sustained effectiveness of occipital nerve stimulation in drug-resistant chronic cluster headache. Headache. 2011;51(8):1191-1201.
- Mueller OM, Gaul C, Katsarava Z, Diener HC, Sure U, Gasser T. Occipital nerve stimulation for the treatment of chronic cluster headache - lessons learned from 18 months experience. Cent Eur Neurosurg. 2011;72(2):84-89.
- Magis D, Bruno, MA, Fumal, A, Gerardy, PY, Hustinx, R, et al. Central modulation in cluster headache patients treated with occipital nerve stimulation: an FDGPET study. BMC Neurol. 2011;11:25.
See the device manual for detailed information regarding the instructions for use, the implant procedure, indications, contraindications, warnings, precautions, and potential adverse events. For further information, contact your local Medtronic representative or consult the Medtronic website at www.medtronic.com