HMS Plus

Hemostasis Management System

HMS Plus Hemostasis Management System

When Measuring the ACT is Not Enough


Heparin and Protamine Management

Medtronic Perfusion Systems remains the pioneer and leader providing both a heparin dose response test and the only point of care heparin assay for individualized heparin and protamine management. Our technology has been identified as a required technology per the 2007 Society of Thoracic Surgeons (STS) guidelines5. The HMS Plus Hemostasis Management System is a reliable, versatile and effective platform for accurate heparin and protamine management1 resulting in lower procedural and operational costs2, 3, 4

HMS Plus Hemostasis Management System

The HMS Plus Hemostasis Management System is a reliable and versatile platform used to perform multiple tests for heparin management. By providing information regarding the individual patient's response to heparin, the HMS Plus System determines the appropriate dose for the patient so that the needed anticoagulant and antithrombotic effect can be achieved.

Benefits of Improved Hemostasis Management

  • Fewer complications associated with excessive blood loss1
  • Preservation of the coagulation system, resulting in fewer transfusions2
  • Fewer surgical reoperations3, thus decreasing associated costs

Manage Your HMS Plus System Data Efficiently and Effectively

  • Stand alone software
  • Easy download of data
  • Documentation for billing and reimbursement
  • QC and patient data management including pre-formatted reports

As part of Medtronic's ongoing commitment to helping you manage your work efficiently and effectively, we offer the HMS Plus EDM, an external data manager to accompany the HMS Plus Hemostasis Management System. By combining this powerful software with the HMS Plus System, you will have access to the reports you'll need to analyze and make informed decisions. This timesaving data management solution offers added convenience, reassurance and confidence – allowing you to stay focused on improving patient outcomes.

The HMS Plus EDM is a versatile Microsoft Access-based data management software application that runs on a PC and is designed to help you manage your patient and QC testing data. All aspects of Microsoft Access software required to run the application are included with the HMS Plus EDM.

Users can select from a list of pre-formatted reports to view the desired information using a variety of sort options.

Ordering Info

HMS Plus System
Order NumberDescription # of Units
30514HMS Plus System is a microprocessor-controlled instrument used to perform multiple tests for anticoagulation management. In addition to activated clotting time (ACT) tests, it allows the user to perform tests to measure actual circulating heparin concentration and assess a patient’s individual response to heparin.1 per box
HMS Plus Cartridges - Each box contains 9 syringes, 9 blunt needles
4 Channel
304-01PORRed - 0.0-0.9 mg/kg9 per box
304-02PORYellow - 0.0-1.5 mg/kg9 per box
304-03PORTan- 1.5-3.0 mg/kg9 per box
304-04PORSilver - 2.0-3.5 mg/kg9 per box
304-05PORBlue - 2.5-4.0 mg/kg9 per box
304-06PORGreen - 3.5-5.0 mg/kg9 per box
304-10PORPurple - 4.5-6.0 mg/kg9 per box
6 Channel
304-07POROrange - 0.0-2.5 mg/kg9 per box
304-08PORGold - 1.5-4.0 mg/kg9 per box
304-09PORWhite - 2.5-5.0 mg/kg9 per box
304-11PORBlack - 3.5-6.0 mg/kg9 per box
304-20PORHeparin Dose Response (HDR) - 6-Channel9 per box
304-30High Range ACT (HR-ACT) - 2-Channel9 per box
HMS Plus Coagulation Controls
Heparin Assay Controls, 10 vials controls, 10 vials deionized water per box
306-01PORRed/Yellow10 per box
306-02PORTan/Silver10 per box
306-03PORBlue/Gold10 per box
306-04PORGreen/White10 per box
306-05POROrange10 per box
306-09PORPurple/Black10 per box
HMS Plus CLOTtrac® Coagulation Controls
Each box contains 15 vials of single-use control and 15 vials deionized water for reconstitution
550-07CLOTtrac® HR Coagulation Control - Verify performance of HMS Plus HRACT Cartridges (304-30) and the HMS Plus15 per box
550-08CLOTtrac® HR Abnormal Coagulation Control - Verify performance of HMS Plus HRACT cartridges (304-30) and the HMS Plus15 per box
550-13CLOTtrac® HR Control Pack (contains both normal and abnormal controls)15 per box
HMS Plus Accessories
HMSPLUSSCBar Code Scanner1 per box
300-01Monoject® Syringes, 3cc100 per box
300-02Blunt Needles, 1-7/16", 19 GA100 per box
313-51HEPtrac® Electronic Control for HMS Plus1 per box
300-04Thermal Printer Paper5 rolls per box
300-10Temperature Verification Cartridge for the HMS Plus1 per box
300-19HMS Plus Cleaning Kit1 per box
30032HMS Plus Cart1 per box
31506HMS Plus Salvage Reservoir Cups100 per box
313-50HEPline Kit1 per box
HMSPLUSEDMHMS Plus External Data Manager Software1 per box



Despotis, GJ, et al. The impact of heparin concentration and activated clotting time monitoring on blood conservation. J Thorac Cardiovascular Surg. 1995;110:46-54.


Hill, AG, et al. More precise heparin and protamine management during cardiopulmonary bypass. Proceedings of the American Academy of Cardiovascular Perfusion. 1990;12-16.


Despotis, GJ, et al. More effective suppression of hemostasis system activation in patients undergoing cardiac surgery by heparin dosing based on heparin blood concentrations rather than ACT. Thromb Haemost. 1996;67:2-8.


Bowie, JE, et al. Automated management of heparin anticoagulation in cardiovascular surgery. Proceedings of the American Academy of Cardiovascular Perfusion. 1985;6:1-5