Female Medtronic TAVR physician meeting with a severe aortic stenosis patient.

SYMPTOMATIC AORTIC STENOSIS CAN‘T WAIT

An urgent evaluation is everything.
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250,000 SSAS PATIENTS

Today, 250,000 people in the U.S. are diagnosed annually with symptomatic severe aortic stenosis (SSAS).1-9

Medtronic TAVR covering 48% of those patients are undertreated nationally which equates to 120,000+ who remain untreated for symptomatic severe aortic stenosis (SAS).
Medtronic transcatheter aortic valve replacement (TAVR) infographic noting that once severe symptoms of symptomatic aortic stenosis appear, survival is cut short.
Medtronic TAVR doctor holding patients hand, after developing symptomatic severe aortic stenosis, the average patient survival is two years without treatment.

MEDICAL MANAGEMENT ISN’T ENOUGH

After developing symptomatic severe aortic stenosis, the average patient survival is two years without treatment. 11

Male Medtronic TAVR patients representing the message symptomatic severe aortic stenosis (SAS) is fatal if left untreated.

SYMPTOMATIC AORTIC STENOSIS CAN BE FATAL

Aortic stenosis is among the most common of all valvular heart diseases and continues to increase as our population ages.12 Symptomatic severe aortic stenosis (SSAS) can be fatal if left untreated.

EARLY DIAGNOSIS AND TREATMENT CAN MEAN BETTER OUTCOMES

Stethoscope image on the Medtronic transcatheter aortic valve replacement (TAVR) page.

DUE TO THE FOLLOWING FACTORS, SSAS ISN'T ALWAYS EASY TO DIAGNOSE:

  • Heart murmurs go undetected.13
  • Referrals are delayed or too late.13
  • Echocardiogram findings are misclassified due to complex cardiac anatomy.13
  • Patients don't recognize or report their symptoms.14
  • Patients refuse treatment.15
Medtronic TAVR graph noting the operated versus unoperated survival rates of aortic valve replacement over a 5-year span.

AORTIC VALVE REPLACEMENT GREATLY IMPROVES THE RATE OF SURVIVAL

Female and male Medtronic TAVR patients able to enjoy time on the beach after transcatheter aortic valve replacement.

Mortality difference for people with symptoms of aortic stenosis treated with aortic valve replacement versus those not undergoing this procedure is one of the most striking in medicine.16

URGENCY IS EVERYTHING FOR SYMPTOMATIC AORTIC STENOSIS PATIENTS

MIND THE MURMUR

You can help save more lives by recognizing the symptoms of SSAS early on.

Infographic for symptomatic aortic stenosis reminding physicians to listen for the murmur, order an echocardiogram, and refer patients to a heart valve team immediately.

REFER YOUR SSAS PATIENTS TO THE HEART VALVE TEAM

FOLLOW AHA/ACC GUIDELINES

AHA/ACC Valvular Heart Disease Guidelines: Class 1 Recommendations: Patients with severe VHD should be evaluated by a multi-disciplinary heart valve team when intervention is considered (Class 1, LOE C).17,18

DOWNLOAD AHA/ACC DECISION TREE

The multi-disciplinary team plays a critical role in the collaborative evaluation, management, and treatment of patients with VHD. Each member of the team brings a perspective and expertise that is fundamental to optimizing patient outcomes.19

AATS/ACC/ASE/SCAI/STS Expert Consensus for Valvular Heart Disease
Male Medtronic physician discussing options with a male patient to get a better understanding of symptomatic aortic stenosis from a patient point-of-view.
Medtronic TAVR infographic noting 90% of patients with heart valve disease are influenced by conversations with their doctor when making symptomatic aortic stenosis treatment decisions.

UNDERSTANDING SYMPTOMATIC AORTIC STENOSIS FROM A PATIENT POINT OF VIEW

It's easier to help patients when you know what they're thinking. The insights gathered from a new national survey conducted by Heart-Valve-Surgery.com, with support from Medtronic, can help you better understand the heart valve patient experience.

Share this resource with your patients: Heart-Valve-Surgery.com can help them learn more about their condition and find a supportive community of other patients diagnosed with SSAS.

1

STS Adult Cardiac Database. 2010 Harvest, Isolated AVR.

2

Bach DS, Cimino N, Deeb GM. Unoperated patients with severe aortic stenosis. J Am Coll Cardiol. November 13, 2007;50(20):2018-2019.

3

Pellikka PA, Sarano ME, Nishimura RA, et al. Outcome of 622 adults with asymptomatic, hemodynamically significant aortic stenosis during prolonged follow-up. Circulation. June 21, 2005;111(24):3290-3295.

4

Charlson E, Legedza AT, Hamel MB. Decision-making and outcomes in severe symptomatic aortic stenosis. J Heart Valve Dis. May 2006;15(3):312-321.

5

Nkomo VT, Gardin JM, Skelton TN, Gottdiener JS, Scott CG, Enriquez-Sarano M. Burden of valvular heart diseases: a population-based study. Lancet. September 16, 2006;368(9540):1005-1011.

6

Lindroos M, Kupari M, Heikkilä J, Tilvis R. Prevalence of aortic valve abnormalities in the elderly: an echocardiographic study of a random population sample. J Am Coll Cardiol. April 1993;21(5):1220-1225.

7

Mack MJ, Brennan JM, Brindis R, et al. Outcomes following transcatheter aortic valve replacement in the United States. JAMA. November 20, 2013;310(19):2069-2077.

8

Medtronic data on file #1. 

9

lung B, Baron G, Butchart EG, et al. A prospective survey of patients with valvular heart disease in Europe: The Euro Heart Survey on Valvular Heart Disease. Eur Heart J. July 2003;24(13):1231-1243. 

10

Bavaria JE. TAVR Update: New Insights and Perspectives from the U.S. National STS/ACC TVT Registry. Available from STS National Database.

11

Lester SJ, Heilbron B, Gin K, Dodek A, Jue J. The natural history and rate of progression of aortic stenosis. Chest. April 1998;113(4):1109-1114.

12

Carabello BA, Paulus WJ. Aortic stenosis. Lancet. March 14, 2009;373(9667):956-966.

13

McCarthy CP, Phelan D, Griffin B. When does asymptomatic aortic stenosis warrant surgery? Assessment techniques. Cleve Clin J Med. April 2016;83(4):271-280.

14

Brennan JM. Under-treatment of Aortic Stenosis in the United States. Presented at TVT 2019; Chicago, IL.

15

Medtronic data on file #2.

16

Schwarz F, Baumann P, Manthey J, et al. The effect of aortic valve replacement on survival. Circulation. November 1982;66(5):1105-1110. 

17

Nishimura RA, Otto CM, Bonow RO, et al. 2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. June 10, 2014;129(23):2440-2492.

18

Nishimura RA, Otto CM, Bonow RO, et al. 2017 AHA/ACC Focused Update of the 2014 AHAJACC Guideline for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. June 20, 2017;135(25):e1159-e1195. 

19

Nishimura RA, O'Gara PT, Bavaria JE, et al. 2019 AATS/ACCIASE/SCAI/STS Expert Consensus Systems of Care Document: A Proposal to Optimize Care for Patients With Valvular Heart Disease: A Joint Report of the American Association for Thoracic Surgery, American College of Cardiology, American Society of Echocardiography, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. J Am Coll Cardiol. May 28, 2019;73(20):2609-2635.

20

Active Living Awareness Initiative Survey. Survey included 3400 respondents. Available at: Heart-Valve-Surgery.com.