Mechanism of injury, associated outcome and intervention

Learn more about rewarming causing cerebral desaturation:

Mechanism of Injury

  • Cerebral Hyperthermia (>37 degrees C) following rewaming during cardiopulmonary bypass and early post-CPB period may increase cerebral metabolic rate increasing risk for cerebral desaturation([FOOTNOTE=Kawahara F, Kadoi Y, Saito S, Goto F, Fujita N. Slow rewarming improves jugular venous oxygen saturation during rewarming. Acta anaesthesiologica Scandinavica. 2003;47(4):419-424.],[ANCHOR=View Abstract],[LINK=/content/mitg/websites/languagemasters/emea/en-gb/support/clinical-evidence.html?id=883109])
  • Evidence suggests that hyperthermia also impairs cerebral autoregulation, potentially exacerbating the potential for neurological injury([FOOTNOTE=Joshi B, Brady K, Lee J, et al. Impaired autoregulation of cerebral blood flow during rewarming from hypothermic cardiopulmonary bypass and its potential association with stroke. Anesthesia and analgesia. 2010;110(2):321-328.],[ANCHOR=],[LINK=])

Associated Outcome

  • Uncontrolled hyperthermia following rewarming during cardiopulmonary bypass and early post-CPB period may lead to worse neurocognitive outcomes([FOOTNOTE=Grigore AM, Murray CF, Ramakrishna H, Djaiani G. A core review of temperature regimens and neuroprotection during cardiopulmonary bypass: does rewarming rate matter? Anesthesia and analgesia. 2009;109(6):1741-1751.],[ANCHOR=View Abstract],[LINK=/content/mitg/websites/languagemasters/emea/en-gb/support/clinical-evidence.html?id=883101])
Intervention % of all interventions([FOOTNOTE=Deschamps A, Lambert J, Couture P, et al. Reversal of decreases in cerebral saturation in high-risk cardiac surgery. Journal of cardiothoracic and vascular anesthesia. 2013;27(6):1260-1266.],[ANCHOR=View Abstract],[LINK=/content/mitg/websites/languagemasters/emea/en-gb/support/clinical-evidence.html?id=805152])
Reduce cerebral oxygen consumption 3

Medtronic Respiratory & Monitoring Solutions EMEA

Provide details to continue

  • Your information will be protected in accordance with our privacy statement.

The site needs to use cookies to store information in your web browser, to make this site work. By clicking “Submit” you consent to the placement of these cookies. Learn more about our cookie policy.