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As healthcare professionals, you are well aware that infants born before completing 37 weeks of pregnancy face significant challenges that demand our utmost attention. These tiny warriors encounter a higher risk of mortality during childhood and could endure a multitude of lifelong health complications.1 It is our collective responsibility to equip ourselves with knowledge and strategies to improve their care pathway. In Europe alone, the statistics are both staggering and concerning.
Approximately 500,000 babies are born prematurely each year in Europe, and these numbers are on the rise.2 Early identification and proactive management in the neonatal intensive care are critical to improving outcomes for vulnerable neonates. One of the most common complications in the neonatal intensive care is bronchopulmonary dysplasia, which is a consequence of premature birth and may require prolonged periods of positive pressure ventilation3. This, in turn, demands vigilant monitoring for associated complications such as infection and early or late sepsis3. At the same time, necrotizing enterocolitis, perinatal asphyxia and congenital malformations are also common neonatal conditions to be promptly managed to avoid deterioration of the infant's condition and decrease the mortality risk.4
Stay ahead - We help you to stay ahead of patient deterioration, by providing you with comprehensive and timely information, ensuring the optimal health outcomes for newborns. Our comprehensive technology covers a wide range of vital signs, including heart rate fluctuations and oxygen saturation level changes, that help the NICU team to anticipate and respond swiftly to evolving clinical scenarios. By staying ahead, we're helping you give these little fighters the best chance at life.
Deliver precise care - We strive to empower you to best care for your little warriors by delivering accuracy and precision, minute-by-minute. Our respiratory devices are designed for the distinct anatomy of neonate airways to maximize comfort and safety for these tiny patients.6
Avoid complications - We arm and equip you to identify, handle, and proactively prevent common complications. With our pioneering patient monitoring and respiratory medical devices, the NICU team can detect early signs of potential complications which can be intervened rapidly before they become life-threatening.9
White paper: Nellcor™ pulse oximetry in NICU
The Nellcor™ pulse oximetry monitoring system should not be used as the sole basis for diagnosis or therapy and is intended only as an adjunct in patient assessment.
The INVOS™ 7100 Cerebral Oximetry System should not be used as the sole basis for diagnosis or therapy and is intended only as an adjunct in patient assessment.
* Patent application - AD No. A0003070US01
† Based on validation data in head-to-head clinical testing compared to MaxN CSR 2021 0312v1 S20-12. RE00357465 RevA
‡ During internal head-to-head bench test compared to MaxN with validated test equipment. RE00368468A00 RevA
¶ Compares the INVOS™ technology to Nonin EQUANOX™*, CASMED FORE-SITE ELITE™*, and Masimo Root™* O3 NIRS monitors during an induced hypoxic state in an animal model.
1. Crump C. Preterm birth and mortality in adulthood: a systematic review. J Perinatol. 2020 Jun;40(6):833-843. doi: 10.1038/s41372-019-0563-y. Epub 2019 Nov 25. PMID: 31767981; PMCID: PMC7246174.
2. Ceurstemont S. Cutting the risks of premature birth. Horizon Magazine. July 30, 2020. Accessed October 9, 2023. https://ec.europa.eu/research-and-innovation/en/horizon-magazine/cutting-risks-premature-birth
3. Salimi U, Dummula K, Tucker MH, Dela Cruz CS, Sampath V. Postnatal Sepsis and Bronchopulmonary Dysplasia in Premature Infants: Mechanistic Insights into "New BPD". Am J Respir Cell Mol Biol. 2022;66(2):137-145. doi:10.1165/rcmb.2021-0353PS
4. Ginglen JG, Butki N. Necrotizing Enterocolitis. [Updated 2023 Aug 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK513357/
5. Haidari ES, Lee HC, Illuzzi JL, Phibbs CS, Lin H, Xu X. Hospital variation in admissions to neonatal intensive care units by diagnosis severity and category. J Perinatol. 2021 Mar;41(3):468-477
6. Kalikkot Thekkeveedu R, El-Saie A, Prakash V, Katakam L, Shivanna B. Ventilation-Induced Lung Injury (VILI) in Neonates: Evidence-Based Concepts and Lung-Protective Strategies. J Clin Med. 2022 Jan 22;11(3):557. doi: 10.3390/jcm11030557. PMID: 35160009; PMCID: PMC8836835.
7. Nellcor™ Pulse Oximetry Performance in Challenging Conditions. Clark R. Baker, Scott McGonigle. Medtronic whitepaper.
8. Based on internal study, A non-GLP comparison study of the INVOS™ NIRS system to competitive regional oxygen systems. 2015.
9. Based on internal white paper #11-PM-0232(1), Cerebral oximetry is frequently a “first alert” indicator of adverse outcomes. April 2016
10. Based on internal testing. Comparative ventilator air leak test performed using the Shiley™ 4.0PCF and 6.5PLCF pediatric tracheostomy tubes with taper-shaped cuff vs. predicate Shiley™ 4.0PDC and 6.5PLC pediatric tracheostomy tubes with barrel-shaped cuff
11. J. Holzki, K Brown, R. Carroll, C. Cote. The anatomy of the pediatric airway: Has our knowledge changed in 120 years? A review of historic and recent investigations of the anatomy of the pediatric larynx. Pediatric Anesthesia. 2017 (28): 13-22.
12. Ho AM, Aun CS, Karmakar MK. The margin of safety associated with the use of cuffed pediatric tracheal tubes. Anesthesia. 2002;57(2):173−175.
13. Wilkes AR. Measuring the filtration performance of breathing system filters using sodium chloride particles. Anaesthesia.2002;57(2):162-168
14. BS EN 13328-1:2001 Breathing system filters for anaesthetic and respiratory use. Salt test method to assess filtration performance
15. EN ISO STANDARD 23328-1:2008 is providing the standard that should be respected by all commercialized devices
16. MHRA Evaluation report 04005 2004 An assesment of 104 breathing systems
17. Watson, Charles & Caroff, Stanley & Rosenberg, Henry. (2021). THE OFFICIAL JOURNAL OF THE ANESTHESIA PATIENT SAFETY FOUNDATION. 36. 41-44.
18. Nelson Labs SN 1122405405-S01 Bacterial Filtration Efficiency (BFE) at an Increased Challenge Level GLP Report
19. Thiessen RJ. The impact of severe acute respiratory syndrome on the use of and requirements for filters in Canada. Respir Care Clin N Am. 2006;12(2):287–306.
20. Thiessen, RJ. Heated expiratory filtration: lessons from the SARS experience. Published 2007. Accessed Feb. 5, 2020.