Safety
There are risks and benefits of DBS: Risks include surgical complications, infection, failure to deliver therapy as needed and/or worsening of some symptoms.
The safety profile observed for aDBS is consistent with the safety profile for cDBS. Stimulation-related side effects are expected during initial aDBS setup, such as worsening of Parkinson’s disease symptoms and dyskinesias, and are expected to resolve with reprogramming. It’s important to ensure patients have regular follow up visits to monitor response to therapy, optimize programming, and manage any stimulation-related side effects promptly, especially within aDBS adjustment and set up periods (at least within the first few months of aDBS programming). aDBS is an optional programming feature and may not work for everyone.