Gain Insight into Brain Response with BIS™ Technology([FOOTNOTE=Dershwitz M. Should we measure depth of anesthesia? Seminars in Anesthesia, Perioperative Medicine and Pain. 2001; 20(4) : 246-256.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=804982])

BIS™ technology offers clinicians added security for providing specialized care and comfort for their patients, including those who may be more sensitive to the haemodynamic effects of anaesthesia.

BIS™ monitoring provides valuable information about the patient status to help clinicians address each patient’s unique anaesthetic requirements.

This technology may be particularly valuable for:

  • Patients with complex conditions whose status may suddenly or frequently change
  • Patients with cardiovascular conditions
  • Obese patients
  • Trauma patients or others requiring reduced levels of anaesthesia

BIS™ Brain Monitoring

Confidently monitor and tailor safe, optimal anaesthesia for each patient with BIS™ brain monitoring.

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Product Features

Designed to measure brain activity in adult patients undergoing general anaesthesia or sedation.

  • The BIS™ Quatro sensor offers:
    • Peel-­and-­stick simplicity
    • Zipprep™ technology
  • BIS™ sensors collect electroencephalograph (EEG) data.
  • BIS™ technology enables simple EEG data collection via a noninvasive sensor applied to the patient’s forehead.

How to Order

For additional information or to place an order, call Customer Service at +44 (0) 19 2320 2504.

Order Information
Order Code Description Unit of Measure Quantity
186-0106 BIS™ 4 Electrode Sensor Each 1
Parameter Description
Sensor dimensions 11 in. x 1.1 in. (approx.)
Weight 3.7 g (approx.)
Weight (packaged) 16.8 g (approx.)
Packaging 25 individually packaged sensors per box
Shelf life One and a half years from date of manufacture
Sensor Element Material Description
Connector (paddle) Polycarbonate plastic (incidental patient contact)
Tab stiffener Polycarbonate sheet (no patient contact)
  One side coated with adhesive
Module Copper/brass/Kapton®* (no patient contact)
Flexible circuit Polyester screen-printed with cured Ag/AgCl and dielectric inks (incidental patient contact)
Electrode gel Potassium chloride (KCl) aqueous gel
Electrode tines disk Green nylon plastic
Electrode sponge disk Polyurethane/polyester foam
Electrode tines retaining disk 1/32 in. white polyethylene foam (no patient contact)
  Both sides coated with medical-grade adhesive
Basepad 1/16 in. white polyethylene foam
  Both sides coated with medical-grade adhesive
Liner card Silicone-coated high-impact polystyrene (no patient contact)
Packaging Paper/aluminum foil/polyethylene (no patient contact)

Order Information

Product Technology

BIS™ monitoring technology provides valuable information about the status of your patients to help address their unique anaesthetic requirements.

How does our sensor technology work to capture the low-­voltage EEG signal?

First, we use a conductive ink that is printed directly on the surface of the sensor, under the adhesive foam and Zipprep™ technology. This creates an electrode surface that is helpful in picking up the low-­voltage EEG.

Second, the Zipprep technology helps clear away the first layer of the epidermis. The mechanical action of pressing on the electrode results in the tines clearing away some of the first layer of dead skin cells, exposing the inner, more electrically conductive layer of skin. The conductive gel within the electrode permeates into this newly exposed area, creating a good electrical pathway between the EEG-­carrying inner layers of skin and the conductive traces within the sensor. The EEG signal is then carried through these traces to the BIS™ monitor.

Third, we include a thin layer of sponge that contains a very precise amount of gel. This gel creates a "bridge" between the forehead and the conductive electrode surface.

These combined components help achieve an optimal environment to acquire and maintain the EEG signal.


"BIS™ monitoring is recommended as an option for all patients receiving total intravenous anaesthetic (TIVA). BIS™ technology is also cost effective in this patient population due to the inability to measure end-tidal anaesthetic concentration."([FOOTNOTE=National Institute for Health and Clinical Excellence. Depth of anaesthesia monitors (E-Entropy, BIS™ and Narcotrend) (DG6). November 2012. Available at: http://guidance.nice.org.uk/DG6.],[ANCHOR=],[LINK=])

– National Institute for Health and Clinical Excellence

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