This multicenter, prospective, single-arm, observational post-market study evaluated the safety and performance of the Evolut R system in a routine hospital setting.
- Study Status/Duration: 12-month outcomes reported/3-year follow-up
- Sample Size: N = 1040
- Devices: Evolut R TAV
1 year hemodynamic data
30-day procedural outcomes
ADVANCE is a multicenter, prospective, single-arm, observational study to evaluate safety and performance of the CoreValve™ system in a routine clinical setting.
Study Status/Duration: 5-year outcomes reported/5-year follow-up
Sample Size: N = 1,015
Devices: CoreValve, TAV
For a summary of all TAVI clinical studies, see Clinical Evidence Compendium
Grube, as presented at EuroPCR 2018
Gerckens U, Tamburino C, Bleiziffer S, et al. Final 5-year clinical and echocardiographic results for treatment of severe aortic stenosis with a self-expanding bioprosthesis from the ADVANCE Study. Eur Heart J. September 21, 2017;38(36):2729-2738.