The importance of hydrophilicity and cellular adhesion1-4

«The ‘race to the surface’, in summary, is a contest between tissue cell integration of, and bacterial adhesion to, an available implant surface.» 

«It is the biomaterial suface then, which does and will select the winner in the ‘race to the surface’»5

Proven Results.
Improving Lives.

Explore more information about enhanced hydrophylicity and other key parameters driving mesh performance.

Hydrophilicity and cell attachment1

The first to reach the surface has a significant advantage.

Interface: Hydrophilicity and cell adhesion2–4,†

Hydrophilic surfaces improve cell adhesion and proliferation.

The ideal mesh

Meshes long term tolerance depends on their physical and mechanical properties.

Smooth and continuous resorbable barriers outperform hydrophobic permanent barriers in preclinical models.

  • † Based on internal data.

  • 1. Based on a NAMSA preclinical study #163905. Symbotex™ composite mesh versus competitors in a pig bowel abrasion
    model. Oct. 2013. 

  • 2. Zelzer M, Majani R, Bradley JW, Rose FR, Davies MC, Alexander MR. Investigation of cell-surface interactions using chemical
    gradients formed from plasma polymers. Biomaterials. 2008;29(2):172–184. 

  • 3. Sannino A, Conversano F, Esposito A, Maffezzoli A. Polymeric meshes for internal sutures with differentiated adhesion on the two
    sides.
    J Mater Sci: Mater Med.2005;16(4):289–296.

  • 4. Lim JI, Yu B, Lee YK. Fabrication of collagen hybridized elastic PLCL for tissue engineering. Biotechnol Lett. 2008;30(12):2085–2090.

  • 5. GristinaAG et al. Med Prog Technol1988-1989; 14(3-4): 205-24.

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