The importance of mechanical properties
in minimizing tissue adhesion1

Dual-Sided Composite Meshes - Minimizing visceral attachment and facilitating tissue ingrowth2,3,†

Proven Results.
Improving Lives.

Explore more information about the importance of mechanical properties and other key parameters driving mesh performance.

Dual-sided composite meshes

Minimizing visceral attachment and facilitating tissue ingrowth2,3,†

Barriers:
Abdominal wall reinforcement:

Resorbable films
(e.g., Collagen, Polyesters)

Macroporous permanent mesh
(e.g., Polyester, Polypropylene)

Complete tissue integration 

Free of extensive inflammation4,†

Symbotex™ Composite Mesh

Comparative performance3,†

Adhesion coverage of mesh surface at 7 days in an animal model.

   

The ideal mesh

Meshes long term tolerance depends on their physical and mechanical properties.

When in contact with viscera, the meshes should be protected by a continous smooth barrier to minimize visceral adhesions.

Smooth and continous resorbable barriers outperform hydrophobic permanent barriers in preclinical models.

  • † Based on preclinical study. Results may not correlate to performance in humans. 

  • 1. Lefranc O, Bayon Y, Montanari S, Gravagna P, Thérin M. Reinforcement materials in soft tissue repair: Key parameters
    controlling tolerance and performance – current and future trends in mesh development, new techniques in genital prolapse
    surgery. Springer London. 2011;275–287.

  • 2. Based on NAMSA Study #198929. Minimizing tissue attachment barrier performance, local tissue effects and tissue integration
    of Parietene™ DS composite mesh in a rat cecal abrasion model. Based on occurrence rates of cecal soft tissue attachment to the
    mesh through macroscopic observations in the rat (n = 18 test articles versus n = 12 bare mesh; p < 0.05). Oct. 2016.

  • 3. Based on internal test report #162750, Evaluating local tissue effects, tissue integration and minimizing tissue attachment
    performance of Symbotex™ composite mesh versus Parietex™ optimized composite mesh. May 2013. 

  • 4. Based on a NAMSA preclinical study #163905. Symbotex™ composite mesh versus competitors in a pig bowel abrasion
    model. Oct. 2013.

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