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Overview

Detect motility disorders

Impedance planimetry testing with Endoflip™ 300 provides real-time measurements of the pressure and dimensions of the esophagus during endoscopic evaluation and surgical procedures.1 Impedance planimetry testing with Endoflip™ 300 is a well-tolerated, convenient way to assess esophageal motility that can inform the need to refer patients to high-resolution manometry.2,3 During surgical procedure, impedance planimetry testing with Endoflip™ 300 gives real-time feedback that can reduce negative outcomes of procedures like Nissen fundoplication, Heller myotomy, and per-oral endoscopic myotomies.4–6

Evaluate motility, minimize discomfort1

Measure pressure and dimensions in the esophagus, pylorus, and anal sphincters with a patient‑friendly solution.

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Up to 50% of endoscopies for predominant esophageal reflux symptoms are negative.7​

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One in three patients referred with ongoing symptoms while using PPIs doesn’t have GERD.8​

No pills

PPI use has been associated with osteoporosis and other risks.9

You need an objective means to help you diagnose GERD and motility disorders​

There are many types of motility disorders, and pinpointing the underlying cause of the patients symptoms can be challenging.10​

Impedance planimetry testing with Endoflip™ 300 can provide information to aid in therapeutic decision making.11

How does Flip™ technology work?

Endoflip™ technology uses high-resolution impedance planimetry to measure luminal geometry and pressure during volume-controlled distension. It helps you assess the mechanical properties of the esophageal wall and opening dynamics of the gastroesophageal junction in various esophageal diseases.​

Literature review

Read a synopsis of clinical publications involving the Endoflip™ impedance planimetry system.

Read review

Our product portfolio 

Endoflip™ 300 impedance planimetry system

Endoflip™ 300 uses a balloon catheter to display diameter estimates of the measurement area in real-time. It can measure and display diameter estimates at up to 16 points within the balloon. 

Endoflip™ 300 helps identify motility disorders by providing real-time pressure and dimension measurements in the esophagus, pylorus, and anal sphincters. 

Endoflip™ 300 provides real-time assessment of the lower esophageal sphincter (LES) myotomy during Heller myotomy or per-oral endoscopic myotomy (POEM) procedures.12

Endoflip™ measurement catheter

The Endoflip™ EF-322N and EF-325N measurement catheters are designed for use with the Endoflip™ impedance planimetry system. They have integrated pressure sensors for balloon pressure measurement.

Esoflip™ dilation catheter

The Esoflip™ ES-310 and ES-320 balloon catheters are indicated for use to dilate esophageal strictures due to esophageal surgery, primary gastroesophageal reflux, or radiation therapy.

The Esoflip™ ES-330 balloon catheter is used in a clinical setting to dilate the gastroesophageal junction (EGJ) to treat achalasia.

The Esoflip™ ES-310 catheter is not suitable for diameter measurements and dilation of strictures smaller than 6 mm or greater than 10 mm.

The Esoflip™ ES-320 catheter is not suitable for diameter measurements and dilation of strictures smaller than 8 mm or greater than 20 mm.

The Esoflip™ ES-330 catheter is not suitable for diameter measurements and dilation of strictures smaller than 8 mm or greater than 30 mm.

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Order Information
ORDER CODE DESCRIPTION UNIT OF MEASURE QUANTITY
EF-300 Endoflip™ impedance planimetry system Each 1
EF-322N Endoflip™ measurement catheter 16 cm Each 1
EF-325N Endoflip™ measurement catheter 8 cm Each 1
ES-320 Esoflip™ dilation catheter 20 mm Box 5/Box
ES-330 Esoflip™ dilation catheter 30 mm Box 5/Box

Order Information

Esophageal portfolio product cleaning guide

Instructions for cleaning esophageal portfolio products

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GI Service plan brochure

Service coverage overview for GI portfolio products

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Transform esophageal care

Our comprehensive solutions can assist you in the assessment and treatment of esophageal patients.

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Patient resources

Find patient information about GERD, acid reflux, and related treatments and therapies.

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Risk information:

Arrhythmia, anaphylaxis, aspiration/inhalation, bacterial infection, bleeding/hemorrhage, death (for Esoflip procedures only), delay to treatment/therapy, dental trauma, dysphagia, gastrointestinal regurgitation (for Esoflip procedures only), heartburn/indigestion (for Esoflip procedures only), hypersensitivity/allergic reaction, laceration of the esophagus, misdiagnosis/misclassification, pain, perforation of the esophagus, thermal burn, vasovagal response.

Resources

  • 1. Endoflip™ 300 Platform Operator's Manual.
  • 2. Carlson, Dustin A., et al. "Esophageal motility classification can be established at the time of endoscopy: a study evaluating real-time functional luminal imaging probe panometry." Gastrointestinal endoscopy 90.6 (2019): 915–923.
  • 3. Farina, Domenico A., and Dustin A. Carlson. "Functional Luminal Imaging Probe (FLIP) as an Adjunctive Modality in Evaluation of Esophageal Dysmotility." Foregut 1.3 (2021): 286–295.
  • 4. Ilczyszyn A, Botha A. Feasibility of esophagogastric junction distensibility measurement during Nissen fundoplication. Dis Esophagus. 2014 Sep-Oct;27(7):637–44.
  • 5. Carlson, Dustin A. "Evaluation of esophageal motility during endoscopy with the functional luminal imaging probe." Techniques in Gastrointestinal Endoscopy 20.3 (2018): 107–113.
  • 6. Hirano, Ikuo, John E. Pandolfino, and Guy E. Boeckxstaens. "Functional lumen imaging probe for the management of esophageal disorders: expert review from the clinical practice updates committee of the AGA institute." Clinical Gastroenterology and Hepatology 15.3 (2017): 325–334.
  • 7. Muthusamy VR, Lightdale JR, Acosta RD, et al. The role of endoscopy in the management of GERD. Gastrointestinal Endoscopy. 2015;81(6):1305-1310. doi: 10.1016/j.gie.2015.02.021. ​
  • 8. Herregods, T. V. K., et al. Patients with refractory reflux symptoms often do not have GERD. Neurogastroenterology & Motility. 2015;27(9):1267-1273.​
  • 9. Vakil, N. Prescribing proton pump inhibitors: is it time to pause and rethink? Drugs. 2012; 72, (4): 437–445 (72):438.​
  • 10. Chaudhury A, Mashimo H. Oropharyngeal & esophageal motility disorders. Current diagnosis & treatment: gastroenterology, hepatology and endoscopy. 2016;3:164.​
  • 11. Ahuja NK, Agnihotri A, Lynch KL. Esophageal distensibility measurement: impact on clinical management and procedure length. Dis Esophagus. 2017 Aug 1;30(8):1–8.
  • 12.  Su B, Dunst C, Gould J, et al. Experience-based expert consensus on the intra-operative usage of the Endoflip impedance planimetry system. Surgical Endoscopy: And Other Interventional Techniques. 2021;35(6):2731-2742. doi:10.1007/s00464-020-07704-3.
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