Reducing Asynchrony

The PAV+™ patient software available on the Puritan Bennett™ 980 ventilator assists clinicians in reducing patient-ventilator asynchrony and improving patient outcomes.

Medtronic Respiratory & Monitoring Solutions EMEA

Reduced Asynchrony

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Improved Sleep

Reduced Effort

Inspiratory Effect

Figure 11. Inspiratory effort (pressure time product at the diaphragm per liter) in patients ventilated with PAV+™ software vs. pressure support under artificially imposed mechanical load (p<0.05).4

Reduced Workload

Reduced Sedative Administration

Figure 14. Mean number of adjustments in sedative administration due to clinical deterioration over 48 hrs. in patients ventilated with PAV+™ software vs. pressure support (p=0.015).6

  • 1. Alexopoulou C, Kondili E, Plataki M, Georgopoulos D. Patient-ventilator synchrony and sleep quality with proportional assist and pressure support ventilation. Intensive care medicine. 2013;39(6):1040-1047.

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  • 2. Bosma K, Ferreyra G, Ambrogio C, et al. Patient-ventilator interaction and sleep in mechanically ventilated patients: pressure support versus proportional assist ventilation. Critical care medicine. 2007;35(4):1048-1054. 

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  • 3. Costa R, Spinazzola G, Cipriani F, et al. A physiologic comparison of proportional assist ventilation with load-adjustable gain factors (PAV+) versus pressure support ventilation (PSV). Intensive care medicine. 2011;37(9):1494-1500.

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  • 4. Kondili E, Prinianakis G, Alexopoulou C, Vakouti E, Klimathianaki M, Georgopoulos D. Respiratory load compensation during mechanical ventilation--proportional assist ventilation with load-adjustable gain factors versus pressure support. Intensive care medicine. 2006;32(5):692-699. 

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  • 5. Xirouchaki N, Kondili E, Vaporidi K, et al. Proportional assist ventilation with load-adjustable gain factors in critically ill patients: comparison with pressure support. Intensive care medicine. 2008;34(11):2026-2034.

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  • 6. Xirouchaki N, Kondili E, Klimathianaki M, Georgopoulos D. Is proportional-assist ventilation with load-adjustable gain factors a user-friendly mode? Intensive care medicine. 2009;35(9):1599-1603.

     View Abstract
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