Gain Easy Access to the Benefits of BIS™ Technology

The BIS™ LoC (Level of Consciousness) 2 channel OEM module delivers the latest performance features of BIS™ brain monitoring technology in a compact, portable, plug-and-play design. With host monitor cable and patient interface cable, uses the proprietary BIS™ algorithm to acquire and process EEG data, displayed as the BIS™ index.

With an integrated clamp for easy mounting, the BIS™ LoC 2 channel OEM module, when integrated into a BIS™-ready patient monitor, provides easy access to the precision and benefits of proven BIS™ brain monitoring technology.


Confidently monitor and tailor safe, optimal anesthesia for each patient with BIS™ brain monitoring.

Find Out How

Product Features

BIS™ Technology:

  • Helps customize anesthetic dosing to individual patient physiologies.
  • Indicates hypnotic effect through the easy-to-read BIS™ index.
  • Facilitates improved patient outcomes as validated in multiple clinical studies.

The BIS™ LoC 2 channel OEM module delivers a full array of BIS™ brain monitoring parameter data, including:

  • BIS™ (Bispectral Index) Value — 0 to 100
  • Signal Quality Indicatory (SQI) — 0 to 100
  • EMG (Electromyograph) Indicator Bar — indicative of muscle activity and other high-frequency artifact
  • EEG Waveform Display — One or two channels of filtered electroencephalogram (EEG) waveforms
  • Suppression Ratio (SR) — 0% to 100% of time over the last 63-second period that the signal is considered to be in the suppressed state, indicating when an isoelectric (flatline) condition may exist.
  • Burst Count – Bursts/Minute — used with BIS™ extended use sensor
  • BIS™ Trend Graph — plots the value of the Bispectral Index™ over time
  • Automated BIS™ Sensor Check — optimized for faster sensor check

How to Order

For additional information or to place an order, call Customer Service at +44 (0) 19 2320 2504.

Order Information
Order Code Description Unit of Measure Quantity
186-0195-SF BISx (Standard Format) Each 1
186-0107 Patient Interface Cable (PIC+) Each 1
186-0202 Replacement Bulkhead Connector Each 1
The following information is provided to the patient monitor by the BISx™ system:
Bispectral Index (BIS™) 0 to 100
Electromyographic Strength (EMG) 30 to 80 dB (where 1 μV2 = 40 dB)
Signal Quality Index (SQI) 0 to 100%
Suppression Ratio (SR) 0 to 100%
Spectral Edge Frequency (SEF) 0.5 to 30.0 Hz
Total Power 40 to 100 dB (where 1 μV2 = 40 dB)
Burst Count 0 to 30 (with an Extend Sensor only)
EEG (Continuous, two channel, real-time EEG waveform) 
Noise (EEG waveform) < 0.3 μV RMS (2.0 μV peak-to-peak): 0.25 Hz to 50 Hz
BIS™ Numeric Update Frequency Once per second
EEG Bandwidth 0.25 Hz to 100 Hz (-3 dB) +/- 10%
Electrode to skin impedances are continuously measured  
Users can select from a range of low-pass and high-pass filters that are available for artifact rejection. The low-pass filters allow the rejection of muscle artifacts. The high-pass filters allow the rejection of ECG signal interference. In addition, a notch filter suppresses line frequency interference.
The BIS™ XP technology built into the BISx system suppresses interference from elecrocautery, EMG and other high frequency noise sources.
Physical Specifications
BISx™ System  
Size 98 mm (3.85 in.) diameter x 63.5 mm (2.5 in.) height (including clamp)
Weight 211 g (7.44 oz) without cables. 434 g (0.96 lb) with cables
Integrated clamp Can accommodate pole up to 32 mm (1.25 in.) in diameter
BISx™ Integral Cables 
Host Monitor Cable 2.7 m (9 ft) with Hypertronics Hypergrip connector
Patient Interface Cable (PIC+) 1.4 m (4.5 ft)
Safety Specifications
The BISx™ system complies with the essential requirements of the Medical Devices Directive 93/42/EEC, as amended by Directive 2007/47/EC, as well as IEC 60601-2 26:2002 and IEC 60601-1-2003. It is a Type BF applied part. It has internal optical coupling and an isolation transformer for patient isolation. It is protected against damage from defibrillation as long as the sensor is not located between the defibrillator pads and is resilient to artifact from electrosurgery.
Data Exchange Summary
The BISx™ system communicates with the host monitor through asynchronous serial communication (RS-232). The protocol is packet oriented with binary data and ACK/NAK handshaking. The host monitor can:
• Choose the communication protocol by an input select line in the host cable
• Request BISx™ hardware and software revision information
• Send commands to the BISx™ system to change smoothing rate (making the BIS™ parameter more or less sensitive to sudden changes in patient measurements), change filter settings and initiate a sensor check
The information specified above in the “Output Parameters” section is transmitted from the BISx™ system to the host once per second. Each of these processed variables packets is 198 bytes long. Additionally, the BISx™ system will transmit EEG waveform data to the host eight times per second. Each of these raw EEG packets is 154 bytes long.
Interface Specifications
BISx™ Host Connector 
Hypertronics Hypergrip connector 12 pin barrel-style connector
Input Power Requirements
The BISx™ system adheres to the power requirements of the USB 1.1 Spec.
Voltage Input +5VDC +/- 5%
Max Current Draw 500 mA
Supply Voltage Ripple <100 mV at all frequencies
Communication Requirements 
Protocol RS-232
RS-232 Communication
Rate 57.6 Kb/sec
Data 8 bit
Stop 1 bit
Parity No
Flow Control None
USB Communication 
Rate Up to 12 Mb/sec
Environmental Specifications
Temperature Range
Operating 0 to 40° C (32 to 104° F)
Storage -10 to 60°C (-50 to 140°F)
Operating 10 to 95% RH at 40°C (104° F), non-condensing
Storage 10 to 95% RH at 60°C (140° F), non-condensing
Altitude Range 
Operating Up to 6,130 m (20,000 ft)
Storage Up to 6,130 m (20,000 ft)

Order Information


"BIS™ monitoring is recommended as an option for all patients receiving total intravenous anesthetic (TIVA). BIS™ technology is also cost effective in this patient population due to the inability to measure end-tidal anesthetic concentration."([FOOTNOTE=National Institute for Health and Clinical Excellence. Depth of anaesthesia monitors (E-Entropy, BIS™ and Narcotrend) (DG6). November 2012. Available at: http://guidance.nice.org.uk/DG6.],[ANCHOR=],[LINK=])

– National Institute for Health and Clinical Excellence