MRI-Guided Laser Ablation
MRI-Guided Laser Ablation
Visualase® provides advanced MRI-guided laser ablation technology for thermal ablation markets, including neurosurgery. Laser energy is delivered to the target area using a laser applicator. As light is delivered through the laser applicator, temperatures in the target area begin to rise, destroying the unwanted tissue.7
Because Visualase procedures are guided by MRI images, the procedure can provide precise ablation. Due to the minimally invasive nature of the procedure, hospital stays have been reported to be reduced compared to open procedures.1-6,8-11
Advantages of Visualase Laser Ablation Technology
A small flexible laser applicator is guided to the intended target area.
The patient is transported to an MRI unit. The MRI allows a physician to precisely monitor treatment using special software to measure temperature changes.
Laser light heats and destroys target area. Temperature maps show the physician the extent of the tissue being destroyed, minimizing risk of potential damage to surrounding healthy tissue.
The laser applicator is removed and the small incision is closed with minimal sutures (typically one stitch).8,10
Visualase uses light energy to destroy soft tissue. Stereotactic laser ablation (SLA) is one of the most recent developments in laser technology.
Visualase utilizes minimally-invasive laser ablation in combination with a powerful image-guided system (MR, MRI) to localize heat to a target and to visualize thermal ablation in real time. Laser light is delivered through the applicator which raises the temperature of the target tissue, irreversibly destroying the targeted tissue.
Carpentier, A., et. al. Real-time magnetic resonance-guided laser thermal therapy for focal metastatic brain tumors. Neurosurgery July 2008; 63:521-529.
Carpentier, A., et. al. MR-guided laser-induced thermal therapy (LITT) for recurrent glioblastomas. Lasers in Surgery and Medicine 2012; 44:361-368.
Curry, D., et. al. MR-guided stereotactic laser ablation of epileptogenic foci in children. Epilepsy & Behavior 2012; 24:408-414.
Esquanazi, Y., et. al. Stereotactic laser ablation of epileptogenic periventricular nodular heterotopia. Epilepsy Research 2014; 108:547-554.
Fabiano, A. and Alberico, R. Laser-interstitial thermal therapy for refractory edema from post-radiosurgery metastasis. World Neurosurgery 2014; 1.E1-1.E4; www.worldneurosurgery.org.
Gonzalez-Martinez, J., et. al. Robot-assisted stereotactic laser ablation in medically intractable epilepsy: operative technique. Neurosurgery Publish Ahead of Print 2014; DOI: 10.1227/NEU.0000000000000286.
Hawasli, A., et al. Magnetic resonance imaging-guided focused laser interstitial thermal therapy for intracranial leasions: Single-institution series. Neurosurgery Dec 2013; 73(6): 1007-1017.
Jethwa, P., et. al. Treatment of a supratentorial primitive neuroectodermal tumor using magnetic resonance-guided laser-induced thermal therapy. J Neurosurg Pediatrics 2011; 8:468-475.
Rao, M., et. al. Magnetic resonance-guided laser ablation improves local control for post-radiosurgery recurrence and/or radiation necrosis. Neurosurgery Publish Ahead of Print 2014; DOI: 10.1227/NEU.0000000000000332.
Torres-Reveron, J., et. al. Stereotactic laser induced thermotherapy (LITT): a novel treatment for brain lesions regrowing after radiosurgery. J Neuroncol 2013; 113:495-503.
Wilfong, A. and Curry, D. Hypothalamic hamartomas: Optimal approach to clinical evaluation and diagnosis. Epilepsia 2013; 54(Suppl. 9): 109-114.