COLORECTAL
CANCER —
TREATABLE,
BEATABLE,  
WITH EARLY
DIAGNOSIS.


 The American Cancer Society recommends that adults begin CRC screening at age 45 years.1

 

Despite evidence that screening reduces colorectal cancer (CRC) incidence and mortality, 40% of age-eligible adults are not up to date on CRC screenings.2

Be part of the solution. Act now and talk to your doctor about getting screened.

What You Need to Know About Colorectal Cancer

  • CRC is the third most common cause of cancer and the second leading cause of cancer death in the US.1,2

  • Most colorectal cancers start as a growth on the inner lining of the colon or rectum, called a polyp. Not all polyps are cancerous, but some can develop into cancer.3

  • One screening option is a colonoscopy. "A colonoscopy provides direct visualization of the entire colon and allows for early detection (screening) and immediate removal of pre-cancerous colorectal polyps (prevention) or early cancers (treatment)."4

  • A screening colonoscopy may reduce the CRC mortality by 60-70%.1

  • There are several screening options, but the best screening test is the one that gets done.5

CRC is on the rise for young adults1

  • In the US, approximately 12% of colorectal cancer cases are diagnosed in individuals under age 50.6

  • It is estimated by 2030, more than 1 in 10 colon cancers will be diagnosed in people under 50 years of age.7

  • Risk factors for early development of colorectal cancer include smoking, alcohol intake, obesity, male, black, Asians and family history of colorectal cancer.1

  • "Guidelines recommend screening at an earlier age for individuals with a family history of CRC and personal history of inflammatory bowel disease (IBD)."8

Early detection matters. Listen to patients colorectal cancer stories.

Brook's story

"It's a huge disease, it's growing in young people and it's preventable, totally preventable."

- Brook, Colon Cancer Survivor

Patrick's story

"Go and screen. It's the smartest thing anyone could do, is eliminate a problem before it occurs."

- Patrick, Colon Cancer Survivor

Helen's story

"If you're 45 or older, you have to get this test. Because if you have a polyp, and they remove the polyp, you’re not going to get the cancer from that polyp. It’s not debatable."

- Helen, Colon Cancer Survivor

These testimonials relate to each individual's experience, thoughts, and opinions. Their accounts are genuine, typical, and documented.
Please talk to your doctor regarding this important topic.

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Understand Your Risk

Complete this assessment to identify your risk level for colon cancer. Then share the results with your doctor.
 

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KNOW the colorectal cancerrisk factors and symptoms

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OBESITY
"Increased waist circumference in adulthood alone is associated with a 53% increased risk of colon cancer."9

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FAMILY HISTORY
A family history of CRC in first degree relatives are associated with a higher risk of CRC.1

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INFLAMMATORY BOWEL DISEASE
"Crohn’s disease (CD) and ulcerative colitis (UC) are chronic inflammatory conditions that are known to increase the risk of colorectal cancer (CRC)."10

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LIFESTYLE
Poor diet, alcohol consumption, smoking, and a lack of physical activity contribute to risk of colon cancer.11

Get screened for yourself and for your family

African Americans have an increased risk of colorectal cancer and death from CRC as compared to other races.12  Yet screening among the African Americans remains low.13  Contact a gastroenterologist and make an appointment for colon screening.   

Ask your doctor about GI Genius

The GI Genius™ intelligent endoscopy module enables computer-assisted detection of polypsduring colonoscopy. It helps the physician detect polyps that may become cancerous through enhanced visualization during colonoscopy.14

Adenoma detection rates differ widely among endoscopists.17 Studies show that endoscopists with higher adenoma detection rates (ADR) during screening colonoscopy more effectively protect their patients from colorectal cancer.16

The GI Genius™ intelligent endoscopy module increases the potential for finding precancerous polyps during colonoscopy — and may reduce the risk of missing it, too.14

The application of artificial intelligence (AI) within colonoscopies is beneficial to colon cancer screening.15 Finding more polyps reduces your chance of getting colorectal cancer16 — giving you greater piece of mind.

INDICATIONS

GI Genius™ intelligent endoscopy module is a computer-assisted reading tool designed to aid endoscopists in detecting colonic mucosal lesions (such as polyps and adenomas) in real time during standard white-light endoscopy examinations of patients undergoing screening and surveillance endoscopic mucosal evaluations. The GI Genius computer-assisted detection device is limited for use with standard white-light endoscopy imaging only. This device is not intended to replace clinical decision making.

RISK INFORMATION

  • GI Genius™ intelligent endoscopy module is intended to be used as an accessory to colonoscopy procedures and is not intended to replace endoscopist assessment or histopathological sampling.
  • The system does not perform any diagnosis and is not intended to be used as a stand-alone diagnostic device
  • The device has not been studied in patients with Inflammatory Bowel Disease (IBD), history of Colorectal cancer, or previous colonic resection. The device performance may be negatively impacted by mucosal irregularities such as background inflammation from certain underlying diseases.
  • Use of GI Genius™ intelligent endoscopy module during colonoscopy may present risks related to identification of lesions. Risk of identification of a false lesion may result in unnecessary patient treatment; or failure to identify a lesion resulting in delayed patient treatment.
  • All medical procedures carry risks. Please refer to your physician for more information about procedure risks related to colonoscopy and those related to GI Genius™ intelligent endoscopy module.
*

Learn more about symptoms at www.cancer.org

1

Ahmed M. Colon Cancer: A Clinician’s Perspective in 2019. Gastroenterology research. 2020;13(1):1-10

2

Muthukrishnan M, Arnold LD, James AS. Patients’ self-reported barriers to colon cancer screening in federally qualified health center settings. Preventive Medicine Reports. 2019;15.

3

Patel K, Li K, Tao K, et al. A comparative study on polyp classification using convolutional neural networks. PLoS ONE. 2020;15(7):1.

4

King-Marshall EC, Mueller N, Dailey A, et al. “It is just another test they want to do”: Patient and caregiver understanding of the colonoscopy procedure. Patient Education and Counseling. 2016;99(4):651-658.

5

Allison JE. The best screening test for colorectal cancer is the one that gets done well. Gastrointestinal endoscopy. 2010;71(2):342-345

6

Siegel RL, Miller KD, Goding Sauer A, et al. Colorectal cancer statistics, 2020. CA Cancer J Clin.3. 2020;70(3):145-164.

7

Bailey CE, Hu C-Y, You YN, et al. Increasing disparities in the age-related incidences of colon and rectal cancers in the United States, 1975-2010. JAMA surgery. 2015

8

Gausman V, Dornblaser D, Anand S, et al. Risk Factors Associated With Early-Onset Colorectal Cancer. Clinical Gastroenterology and Hepatology. 2020;18(12):2752-2759

9

Schaberg MN, Smith KS, Greene MW, Frugé AD. Characterizing Demographic and Geographical Differences in Health Beliefs and Dietary Habits Related to Colon Cancer Risk in US Adults. Frontiers in nutrition. 2020;7:568643

10

Lopez A, Collet-Fenetrier B, Belle A, Peyrin-Biroulet L. Patients’ knowledge and fear of colorectal cancer risk in inflammatory bowel disease. Journal of digestive diseases. 2016;17(6):383-391.

11

Johnson CM, Wei C, Ensor JE, et al. Meta-analyses of colorectal cancer risk factors. Cancer causes & control : CCC. 2013;24(6):1207-1222.

12

DeSantis CE, Siegel RL, Sauer AG, et al. Cancer statistics for African Americans, 2016: Progress and opportunities in reducing racial disparities. CA: A Cancer Journal for Clinicians. 2016;66(4):290

13

Earl V, Beasley D, Ye C, et al. Barriers and Facilitators to Colorectal Cancer Screening in African-American Men. Digestive Diseases and Sciences. 2021:1

14

Repici A, Badalamenti M, Maselli R, et al. Efficacy of real-time computer-aided detection  of colorectal neoplasia in a randomized trial. Gastroenterology. 2020; 159:512–520.e7.

15

Stockenhuber K, East JE. Colorectal cancer: prevention and early diagnosis. Medicine. 2019;47(7):395-399

16

Corley DA, Jenson CD, Marks AR JR, et al. Adenoma Detection Rate and Risk of Colorectal Cancer and Death. The New England Journal of Medicine. 2014; 370: 2539–2541.

17

Joseph J, LePage EM, Cheney CP, Pawa R. Artificial intelligence in colonoscopy. World journal of gastroenterology. 2021;27(29):4802-4817.

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