CHITOGEL

Endoscopic Sinus Surgery Kit

Chitogel is a dissolvable biomaterial made with a unique combination of natural ingredients, clinically proven to enhance wound healing and minimize ostial stenosis after sinus surgery.

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Syringe full of Chitogel is held by a gloved hand

OVERVIEW

Chitogel emerges from the tip of a syringe being pressed by a gloved hand

A NATURAL POSTOPERATIVE DRESSING
FROM A TRUSTED LEADER

Optimizing wound healing after sinus surgery is critical to achieving long-term, positive outcomes.  It requires a solution that minimizes adhesions, preserves structural integrity, and addresses patient comfort.  Medtronic is meeting these needs with Chitogel — a dissolvable biomaterial made with a unique combination of natural ingredients and clinically proven to enhance wound healing.4

PRODUCT DETAILS

THREE KEY INGREDIENTS ENHANCE WOUND HEALING

Chitogel supports critical wound healing after sinus surgery by combining chitosan, dextran, and glycerol — all derived from natural resources.

Diagram of the three key Chitogel ingredients that enhance wound healing: chitosan, dextran aldehyde, and glycerol

 

  • Chitosan has anti-adhesion and hemostatic properties.1

  • Dextran inhibits coagulation factors and reduces fibroblast migration.2,3

  • Glycerol retains moisture and keeps the gel soft.

BACKED BY EXPERIENCE AND EVIDENCE

Chitogel's development is backed by 10 years of research and clinical evidence, 18 published studies and papers, and successful patient outcomes of a diverse range of sinus surgeries.

DEMONSTRATED
WOUND-HEALING CHARACTERISTICS*4

Chitogel achieves a 50% reduction in granulation tissue formation, edema, and crust formation, along with a 47% reduction in adhesions.

OSTIAL-AREA IMPROVEMENTS*4

Chitogel achieves significant ostial-area improvements, including 73% frontal, 35% sphenoid, and 34% maxillary.

AN ADJUNCT TO THE NATURAL HEALING PROCESS

Chitogel emerges from the tip of a syringe being pressed by a gloved hand

Chitogel’s unique characteristics make it an ideal nasal dressing for sinus surgery needs.

Use it to:

  • Separate tissue or structures compromised by surgical trauma.
  • Prevent adhesions between mucosal surfaces in the nasal cavity.
  • Minimize ostial stenosis.
  • Control minimal bleeding by tamponade effect, blood absorption, and platelet aggregation.
  • Enhance wound healing.

OPTIMIZED HIGH-VISCOSITY GEL FORMULA

Chitogel being squeezed out of a clear tube onto a white surface

 

  • Remains in place after application
  • Allows for consistent postoperative nasal irrigation
  • Clears naturally post-surgery
  • Resides in the sinus cavity for up to two weeks

EASILY APPLIED, EASY ON YOUR PATIENTS

Chitogel syringe held up for display in a pair of gloved hands

Unlike traditional post-surgical nasal packing products, which can be associated with an unpleasant patient experience, Chitogel is a soft, pliable, viscous gel that is applied with a malleable applicator. It helps minimize bleeding and comfortably coats the affected area.

Benefits include:

  • Conforms effortlessly to mucosal surfaces
  • Separates tissues in a wide range of sinus anatomies and surgeries
  • Remains in place during the critical healing period

CHITOGEL

BROCHURE

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*

At 12 months post-surgery.

1

Athanasiadis, T., Beule, et al. Effects of a novel chitosan gel on mucosal wound healing following endoscopic sinus surgery in a sheep model of chronic rhinosinusitis. Laryngoscope. 2008 Jun;118(6):1088-94.

2

E. Polifka, Janine & Habermann, Juliane. “Anticoagulants, thrombocyte aggregation inhibitors, fibrinolytics and volume replacement agents.” Drugs During Pregnancy and Lactation: Treatment Options and Risk Assessment: Third Edition. 2015; 225-249.

3

Paramasivan, S., Jones, et al. The use of chitosan-dextran gel shows anti-inflammatory, antibiofilm, and antiproliferative properties in fibroblast cell culture”. Am J Rhinol Allergy. 2014 Sep-Oct;28(5):361-5.

4

Ha T, Valent onide chitosan gel on wound healing following endoscopic sinus surgery. Int Forum Allergy Rhinol. 2018 Mar;8(3):435-443.