Choosing a treatment option for managing severe spasticity depends on the severity of symptoms and efficacy of the current therapy as determined during the patient assessment process. Treatment typically begins with noninvasive therapies and, if unsuccessful, moves to more interventional treatment options. Often, several therapies are used together for optimum benefit to the patient.
Severe spasticity can be treated separately from the patient's primary underlying condition. Effective treatment of spasticity may:
In many cases, severe spasticity may be adequately managed with oral medication, rehabilitative interventions, and/or injection therapy. For some patients, however, these treatments do not provide sufficient relief, or they result in intolerable side effects. For example, oral drugs at effective doses for managing spasticity may cause severe drowsiness, dizziness, weakness, and nausea, which can limit participation in family, social, academic, and/or work-related activities.
ITB Therapy with Lioresal® Intrathecal (baclofen injection) for the management of severe spasticity should be considered for patients who first respond to a screening dose prior to consideration for long term infusion via an implantable pump.
Lioresal® intrathecal is not recommended for intravenous, intramuscular, subcutaneous, or epidural administration. Hypersensitivity to oral baclofen is a contraindication to the therapy.
Use ITB Therapy with care in patients who:
Safety and effectiveness in pediatric patients below the age of 4 have not been established.
For important safety information, including BOXED WARNING, please refer to Lioresal® Intrathecal (baclofen injection) full prescribing information at lioresal.com/prescribing information.
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Common Adverse Reactions
Serious Adverse Reactions
For more information, including BOXED WARNING, refer to Lioresal® Intrathecal (baclofen injection) prescribing information, located at lioresal.com/prescribinginformation.
For full prescribing information of Lioresal® Intrathecal (baclofen injection), including BOXED WARNING, please refer to Lioresal® Intrathecal (baclofen injection) full prescribing information at lioresal.com/prescribinginformation.