Vascular conditions

Vein disease

Break free from leg pain and varicose veins.

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Leg vein disease, or chronic venous insufficiency (CVI), occurs when the blood in the veins doesn't flow back to the heart but flows backward instead (referred to as reflux) when a diseased vein is left untreated. Depending on the severity of the disease this can cause symptoms such as spider veins, varicose veins, discoloration, swelling, heaviness, raised veins, and leg ulcers.

Vein disease is common — you are not alone.

Vein disease can affect anyone, regardless of age, gender, or race. More than 190 million people have CVI or varicose veins globally.2 In the United States, more than 30 million people suffer from varicose veins or CVI, yet the majority remain undiagnosed and untreated.*1

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30 million
people in the United States with CVI or varicose veins*1

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2 million
seek treatment each year*1

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receive treatment each year*1

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*Statistics based on individuals over the age of 40.

Medtronic is here to help you break free from leg pain and unsightly varicose veins caused by vein disease — so you can get back to feeling good again.

Understanding vein disease

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Varicose veins are not just a cosmetic issue. Leg vein disease can cause varicose veins and other painful symptoms that can impact how you live.

Exploring treatment options

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Treating vein disease and varicose veins with Medtronic procedures is easier than you may think.

Finding a doctor

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Use this search tool to find a doctor who offers the VenaSeal™ procedure or ClosureFast™ procedure from Medtronic.

Check your symptoms.

Think you’re experiencing vein disease?

Use our quick symptom checker to assess what's going on and learn how you could feel better. The journey to feeling good again starts here.

Common vein disease questions

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What causes leg vein disease?

Healthy veins in the legs have valves that allow blood to flow in the direction of the heart. Vein disease develops when the valves stop working properly and cause blood to flow backward and pool in the lower leg veins, which is known as venous reflux.2

How do I know if I have leg vein disease?

What are my treatment options?

How long will the treatment last?

How do I find a doctor to help me?

What does recovery look like?

Does health insurance cover treatment?

Find a vein disease doctor or clinic near you.

Enter your ZIP code to find a doctor who uses Medtronic VenaSeal or ClosureFast procedure treatments.



Gloviczki P, Comerota AJ, Dalsing MC, et al. The care of patients with varicose veins and associated chronic venous diseases: Clinical practice guidelines of the Society for Vascular Surgery and the American Venous Forum. J Vasc Surg. May 2011;53(5 Suppl):2S–48S.


Strategic Market Assessment: Chronic Venous Insufficiency, Dymedex Consulting, LLC, November 2014.


Chronic Venous Insufficiency. Johns Hopkins Medicine. Available at: Accessed March 28, 2023.


Morrison N, Gibson K, McEnroe S, et al. Randomized trial comparing cyanoacrylate embolization and radiofrequency ablation for incompetent great saphenous veins (VeClose). J Vasc Surg. April 2015;61(4):985–994.


Proebstle T, Alm J, Dimitri S, et al. Three-year follow-up results of the prospective European Multicenter Cohort Study on Cyanoacrylate Embolization for treatment of refluxing great saphenous veins. J Vasc Surg Venous Lymphat Disord. March 2021;9(2):329–334.


Gibson K, Ferris B. Cyanoacrylate closure of incompetent great, small and accessory saphenous veins without the use of post-procedure compression: Initial outcomes of a post-market evaluation of the VenaSeal System (the WAVES Study). Vascular. April 2017;25(2):149–156.


Almeida JI, Javier JJ, Mackay EG, et al. Thirty-sixth month follow-up of first-in-human use of cyanoacrylate adhesive for treatment of saphenous vein incompetence. J Vasc Surg Venous Lymphat Disord. September 2017;5(5):658–666.


Morrison N, Gibson K, Vasquez M, et al. Five-year extension study of patients from a randomized clinical trial (VeClose) comparing cyanoacrylate closure versus radiofrequency ablation for the treatment of incompetent great saphenous veins. J Vasc Surg Venous Lymphat Disord. November 2020;8(6):978–989.


Proebstle TM, Alm BJ, Gockeritz O, et al. Five-year results from the prospective European multicentre cohort study on radiofrequency segmental thermal ablation for incompetent great saphenous veins. Br J Surg. February 2015;102(3):212–218.


Almeida JI, Kaufman J, Gockeritz O, et al. Radiofrequency endovenous ClosureFast procedure versus laser ablation for the treatment of great saphenous reflux: A multicenter, single-blinded, randomized study (RECOVERY Study). J Vasc Interv Radiol. June 2009;20(6):752–759.

Information on this site should not be used as a substitute for talking with your doctor. Always talk with your doctor about diagnosis and treatment information.