How it works

The Medtronic Symplicity blood pressure procedure provides a complementary treatment option for people with high blood pressure (HBP), also known as hypertension.


Illustration of a patient receiving blood pressure check with readings of systolic and diastolic blood pressure shown


What the Symplicity procedure does.

The Symplicity blood pressure procedure calms excessively active nerves near the kidneys that may be contributing to your high blood pressure.1

Expect a safe and effective procedure.2,3

  • Stable kidney function through two years.4
  • > 25,000 people worldwide have received it.5

Adverse events include, but are not limited to, bruising and pain. Results may vary.

One procedure to help lower your blood pressure

The Symplicity blood pressure procedure is done in a hospital, and usually takes about an hour. Some people go home the same day. Others stay overnight. You doctor will decide what is right for you.

Is the Symplicity blood pressure procedure right for you?

Answer a few simple questions then talk to your doctor to see if the procedure may be right for you.

Find a Symplicity specialist.

Here’s how you can find a doctor near you who is experienced in the Symplicity blood pressure procedure.



 Coates P, Tunev S, Trudel J, Hettrick DA. Time, Temperature, Power, and Impedance Considerations for Radiofrequency Catheter Renal Denervation. Cardiovasc Revasc Med. September 2022;42:171–177.


Kandzari DE, Townsend RR, Kario K, et al. Safety and Efficacy of Renal Denervation in Patients Taking Antihypertensive Medications. J Am Coll Cardiol. November 7, 2023;82(19):1809–1823.


Böhm M, Kario K, Kandzari DE, et al. Efficacy of catheter-based renal denervation in the absence of antihypertensive medications (SPYRAL HTN-OFF MED Pivotal): a multicentre, randomized, sham-controlled trial. Lancet. May 2, 2020;395(10234):1444-1451.


Symplicity Spyral™ Renal Denervation System. FDA Presentation. US FDA Circulatory Systems Devices Panel. Meeting date August 23, 2023.


Medtronic data on file. RDN Catheter Historical Data, June 2023. Data include both Symplicity Flex and Symplicity Spyral.


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