Smart MDI Multiple daily injection (MDI) therapy can be complicated. Smart MDI may help.

 Three powerful tools to help your patients stay ahead of their diabetes.

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A patient's MDI journey.

What is Smart MDI?

For people who manage their diabetes with insulin injections, Smart MDI helps relieve the physical and mental effort required, by using an ecosystem of smart-enabled technology devices, to help make your life a bit easier.

Smart MDI includes a continuous glucose monitor (CGM), an injection port, and smart pen products.

If your patient isn't ready for or interested in a pump, Smart MDI offers some of the advantages of insulin pumps while still offering the freedom of daily injections. The Smart MDI family works together to help your patients stay ahead of their diabetes.

Three powerful tools

The Guardian Connect app and sensor transmitter.

Guardian™ Connect system

  • 98.5% low detection accuracy1
    Accuracy when it matters most
  • Predictability up to an hour in advance*
    Extra time to take action
  • Automatic uploads
    The data you want when you need it - Helps avoid wasted appointments

The InPen app and smart insulin pen with the Bluetooth logo.

InPen™ smart insulin pen

  • Shareable reports
    More data = less time waiting
  • Dose reminders
    For those forgotten mealtime shots
  • 12 unit doses
    For those with insulin sensitivity

The i-Port advance injection port.

i-Port Advance™ injection port

  • 93% reduction in needle pokes
    It takes the shots for them
  • Comfortable and dependable
    Helps with compliance
  • Auto-insertion device included
    For those with fear of pokes

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Guardian™ Connect system SSED, page 19, Table 5. 98.5% Glucose Correct Detection Rate based on Predictive Alerts at 30 minutes when worn on the abdomen.


Alerts must be set to receive predictive alerts.

Based on 150 injections per month versus 10 insertions per month

Survey data on file; individual results may vary.

Important Safety Information: Guardian™ Connect CGM System
The Guardian™ Connect system requires a prescription and is indicated for continuous or periodic monitoring of glucose levels in the interstitial fluid under the skin, in patients (14 to 75 years of age) with diabetes mellitus. The system is intended to complement, not replace, information obtained from standard blood glucose monitoring devices, and is not recommended for people who are unwilling or unable to perform a minimum of two meter blood glucose tests per day, or for people who are unable or unwilling to maintain contact with their healthcare professional. The system requires a functioning mobile electronic device with correct settings. If the mobile device is not set up or used correctly, you may not receive sensor glucose information or alerts. For complete details of the system and its components, including warnings, contraindications, and precautions, please consult the user guide at and important safety information.

Important Safety Information for InPen™ Smart Insulin Pen
The InPenTM requires a prescription. It is a home-use reusable pen injector for single-patient use by people with diabetes under the supervision of an adult caregiver, or by a patient age 7 and older for the self-injection of a desired dose of insulin. The pen injector is compatible with Lilly Humalog® U-100 3.0 mL cartridges, Novo Nordisk Novolog® U-100 3.0 mL cartridges, and Novo Nordisk Fiasp® U-100 3.0 mL cartridges and single-use detachable and disposable pen needles (not included). The pen injector allows the user to dial the desired dose from 0.5 to 30 units in one-half (1/2) unit increments.

The InPenTM dose calculator, a component of the InPenTM app, is indicated for the management of diabetes by people with diabetes under the supervision of an adult caregiver, or by a patient age 7 and older for calculating an insulin dose or carbohydrate intake based on user entered data.

For an insulin dose based on amount of carbohydrates, a healthcare professional must provide patient-specific target blood glucose, insulin-to-carbohydrate ratio, insulin sensitivity parameters, and duration of insulin action to be programmed into the software prior to use as it is required for set up.

For an insulin dose based on fixed/variable meal sizes, a healthcare professional must provide patient-specific fixed doses/meal sizes to be programmed into the software prior to use.

For additional product and important safety considerations, see User Guide and

Important Safety Information: i-Port Advance™ Injection Port
i-Port AdvanceTM injection port is prescription-indicated for patients who administer, or to whom is administered, multiple daily subcutaneous injections of physician prescribed medications, including insulin. The device may remain in place for up to 72 hours to accommodate multiple drug injections without the discomfort of additional needle sticks. Site infection and/or irritation is a risk. Patients experiencing such symptoms should immediately consult their healthcare provider and/ or discontinue use. For complete details, please consult i-PortTM Advance product user guide.