Outcomes | Ventilator-Associated Pneumonia | Medtronic

Mortality Rates in Patients with VAP Versus Controls

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Mortality Rates in Patients with VAP Versus Controls

	VAP Mortality	Control Mortality	Difference
Bercault 2001([FOOTNOTE=Bercault N, Boulain T. Mortality rate attributable to ventilator-associated nosocomial pneumonia in an adult intensive care unit: a prospective case-control study. Crit Care Med. 2001;29(12):2303-2309. ],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=805224]) (p< 0.0001)	41.00%	14.00%	27.00%
Warren 2003([FOOTNOTE=Warren DK, Shukla SJ, Olsen MA, et al. Outcome and attributable cost of ventilator-associated pneumonia among intensive care unit patients in a suburban medical center. Crit Care Med. 2003;31(5):1312-1317.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=277904]) (p< 0.001)	50.00%	34.00%	16.00%
Rello 2002([FOOTNOTE=Rello J, Ollendorf DA, Oster G, et al. Epidemiology and outcomes of ventilator-associated pneumonia in a large US database. Chest. 2002;122(6):2115-2121.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=805225]) (p< 0.713)	30.50%	30.40%	0.10%
Ibrahim 2001([FOOTNOTE=Ibrahim EH, Tracy L, Hill C, Fraser VJ, Kollef MH. The occurrence of ventilator-associated pneumonia in a community hospital: risk factors and clinical outcomes. Chest. 2001;120(2):555-561. ],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=805222]) (p< 0.004)	45.50%	32.20%	13.30%
Kollef 2005([FOOTNOTE=Kollef MH, Shorr A, Tabak YP, Gupta V, Liu LZ, Johannes RS. Epidemiology and outcomes of health-care-associated pneumonia: results from a large US database of culture-positive pneumonia. Chest. 2005;128(6):3854-3862.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=805226]) (p< 0.0001)	29.30%	10.00%	19.30%

VAP - Attributable Mortality at 30 and 60 Days

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VAP - Attributable Mortality at 30 and 60 Days

	Attributable Mortality
Bekaert 2011([FOOTNOTE=Bekaert M, Timsit JF, Vansteelandt S, et al. Attributable mortality of ventilator-associated pneumonia: a reappraisal using causal analysis. Am J Respir Crit Care Med. 2011;184(10):1133-1139. ],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=476875]) (30 Day)	4.40%
Bekaert 2011⁶ (60 Day)	5.90%

Hospital Length of Stay (LOS) May Increase in Patients with VAP Versus Controls

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Hospital Length of Stay (LOS) May Increase in Patients with VAP Versus Controls

	VAP Hospital LOS	Control Hospital LOS	Difference
Warren 2003² (p< 0.001)	38	13	25
Rello 2002³ (p< 0.001)	25.5	14	11.5
Kollef 2005⁵ (p< 0.0001)	23	7.5	15.5

ICU Length of Stay (LOS) May Increase in Patients with VAP Versus Controls

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ICU Length of Stay (LOS) May Increase in Patients with VAP Versus Controls

	VAP ICU LOS	Control ICU LOS	Difference
Bercault 2001¹ (p< 0.0001)	31	26	5
Warren 2003² (p< 0.001)	26	4	22
Rello 2002³ (p< 0.001)	11.7	5.6	6.1

Hospital Costs May Increase in Patients with VAP Versus Controls

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Hospital Costs May Increase in Patients with VAP Versus Controls

	VAP Costs	Control Costs	Difference
Warren 2003² (p< 0.001)	$70,568	$21,620	$48,948
Rello 2002³ (p< 0.001)	$104,983	$63,689	$41,294
Kollef 2005⁵ (p< 0.0001)	$150,841	$25,218	$125,623
Hugonnet 2004([FOOTNOTE=Hugonnet S, Eggimann P, Borst F, Maricot P, Chevrolet JC, Pittet D. Impact of ventilator-associated pneumonia on resource utilization and patient outcome. Infect Control Hosp Epidemiol. 2004;25(12):1090-1096.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=277906]) (p< 0.001)	$24,727	$17,438	$7,289