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Medtronic Clinical Solutions Ventilator-Associated Pneumonia Outcomes

Ventilator-Associated Pneumonia
  • Incidence
  • Outcomes
  • Pathogenesis
  • Interventions
  • Guidelines

Outcomes

VAP is associated with increased mortality, length of stay and costs.

Mortality Rates in Patients with VAP Versus Controls

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Mortality Rates in Patients with VAP Versus Controls
  VAP Mortality Control Mortality Difference
Bercault 2001([FOOTNOTE=Bercault N, Boulain T. Mortality rate attributable to ventilator-associated nosocomial pneumonia in an adult intensive care unit: a prospective case-control study. Crit Care Med. 2001;29(12):2303-2309. ],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=805224]) 
(p< 0.0001)
41.00% 14.00% 27.00%
Warren 2003([FOOTNOTE=Warren DK, Shukla SJ, Olsen MA, et al. Outcome and attributable cost of ventilator-associated pneumonia among intensive care unit patients in a suburban medical center. Crit Care Med. 2003;31(5):1312-1317.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=277904])
(p< 0.001)
50.00% 34.00% 16.00%
Rello 2002([FOOTNOTE=Rello J, Ollendorf DA, Oster G, et al. Epidemiology and outcomes of ventilator-associated pneumonia in a large US database. Chest. 2002;122(6):2115-2121.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=805225]) 
(p< 0.713)
30.50% 30.40% 0.10%
Ibrahim 2001([FOOTNOTE=Ibrahim EH, Tracy L, Hill C, Fraser VJ, Kollef MH. The occurrence of ventilator-associated pneumonia in a community hospital: risk factors and clinical outcomes. Chest. 2001;120(2):555-561. ],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=805222]) 
(p< 0.004)
45.50% 32.20% 13.30%
Kollef 2005([FOOTNOTE=Kollef MH, Shorr A, Tabak YP, Gupta V, Liu LZ, Johannes RS. Epidemiology and outcomes of health-care-associated pneumonia: results from a large US database of culture-positive pneumonia. Chest. 2005;128(6):3854-3862.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=805226]) 
(p< 0.0001)
29.30% 10.00% 19.30%

VAP - Attributable Mortality at 30 and 60 Days

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VAP - Attributable Mortality at 30 and 60 Days
  Attributable Mortality
Bekaert 2011([FOOTNOTE=Bekaert M, Timsit JF, Vansteelandt S, et al. Attributable mortality of ventilator-associated pneumonia: a reappraisal using causal analysis. Am J Respir Crit Care Med. 2011;184(10):1133-1139. ],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=476875]) 
(30 Day)
4.40%
Bekaert 20116 
(60 Day)
5.90%

Hospital Length of Stay (LOS) May Increase in Patients with VAP Versus Controls

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Hospital Length of Stay (LOS) May Increase in Patients with VAP Versus Controls
  VAP Hospital LOS Control Hospital LOS Difference
Warren 20032
(p< 0.001)
38 13 25
Rello 20023
(p< 0.001)
25.5 14 11.5
Kollef 20055
(p< 0.0001)
23 7.5 15.5

ICU Length of Stay (LOS) May Increase in Patients with VAP Versus Controls

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ICU Length of Stay (LOS) May Increase in Patients with VAP Versus Controls
  VAP ICU LOS Control ICU LOS Difference
Bercault 20011
(p< 0.0001)
31 26 5
Warren 20032
(p< 0.001)
26 4 22
Rello 20023
(p< 0.001)
11.7 5.6 6.1

Hospital Costs May Increase in Patients with VAP Versus Controls

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Hospital Costs May Increase in Patients with VAP Versus Controls
  VAP Costs Control Costs Difference
Warren 20032
(p< 0.001)
$70,568 $21,620
$48,948
Rello 20023 
(p< 0.001)
$104,983 $63,689 $41,294
Kollef 20055 
(p< 0.0001)

$150,841 $25,218 $125,623
Hugonnet 2004([FOOTNOTE=Hugonnet S, Eggimann P, Borst F, Maricot P, Chevrolet JC, Pittet D. Impact of ventilator-associated pneumonia on resource utilization and patient outcome. Infect Control Hosp Epidemiol. 2004;25(12):1090-1096.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=277906]) 
(p< 0.001)
$24,727 $17,438 $7,289

Bibliography of VAP Evidence

View a list of studies used on this site.

View Bibliography
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